Sodium 4-Aminosalicylate Dihydrate
- CAS No.6018-19-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Sodium 4-Aminosalicylate Dihydrate (CAS 6018-19-5), a key pharmaceutical intermediate used in the synthesis of anti-tuberculosis therapeutics.
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Product Overview
Sodium 4-Aminosalicylate Dihydrate is a high-quality pharmaceutical intermediate with the molecular formula C7H10NNaO5 and a molecular weight of 211.148. It appears as a white to off-white crystalline powder and is widely utilized in the production of active pharmaceutical ingredients (APIs) targeting mycobacterial infections. This compound is not classified as dangerous goods for transport and complies with international safety standards for chemical handling and storage.
Specifications
| Appearance | White or off-white crystalline powder |
|---|---|
| Purity (HPLC) | ≥98.5% |
| Color | ≤B5 |
| pH | 6.5–8.5 |
| M-Aminophenol | ≤0.1% |
| 5-Aminosalicylic Acid | ≤1.0% |
| Single Impurity | ≤0.1% |
| Total Impurity | ≤1.0% |
| Heavy Metals | ≤10 ppm |
| Loss on Drying | 16.0–17.5% |
| Assay | 90.0–101.0% |
| Melting Point | 250 °C |
| Boiling Point | 380.8 °C at 760 mmHg |
| Flash Point | 184.1 °C |
Industrial Applications
As a critical building block in advanced organic synthesis, Sodium 4-Aminosalicylate Dihydrate serves primarily as an intermediate in the manufacture of anti-tuberculosis medications. It is employed in multi-step synthetic routes to produce complex pharmaceutical APIs designed for the comprehensive treatment of various forms of tuberculosis. Its high chemical purity and stringent impurity profile ensure reliability and consistency in downstream drug formulation processes.
Key advantages include:
- Consistent batch-to-batch quality suitable for GMP-compliant API production
- Low levels of specified and unspecified impurities
- Stable physical and chemical properties under standard storage conditions
- Compatibility with large-scale industrial synthesis workflows
For optimal stability, store in a cool, dry, and well-ventilated area with the container tightly closed. Standard packaging is 25 kg per drum, with custom packaging available upon request.
