Intermediates

tert-Butyl bromoacetate

  • CAS No.5292-43-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade tert-Butyl bromoacetate serving as a vital alkylating agent for pharmaceutical and peptide synthesis applications.

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Product Technical Details

Product Overview

tert-Butyl bromoacetate is a highly specialized organic intermediate widely recognized for its versatility in fine chemical synthesis. As a key ester derivative, it functions primarily as an effective alkylating agent within complex pharmaceutical manufacturing processes. Our facility produces this compound under strict quality control standards to ensure consistent performance in downstream reactions, particularly those involving the construction of amino acid structures and peptide chains.

The chemical stability provided by the tert-butyl group makes this substance an invaluable building block for protecting group strategies in organic synthesis. Manufacturers relying on precise molecular architecture benefit from the high purity levels we maintain, which minimize side reactions and improve overall yield in multi-step synthesis routes.

Technical Specifications

ParameterSpecification
CAS Number5292-43-3
Molecular FormulaC6H11BrO2
Molecular Weight195.05 g/mol
AppearanceColorless to slightly yellow transparent liquid
Purity (GC)≥98.0%
Moisture Content≤0.1%
Density1.338 g/cm3
Boiling Point50oC
Flash Point121oC
Refractive Index1.445

Industrial Applications

This intermediate is predominantly utilized in the pharmaceutical and biotechnology sectors. Its primary role involves facilitating the synthesis of specialized amino acids and peptide compounds, which are essential components in modern therapeutic development. The compound acts as a reliable source of the bromoacetyl moiety, enabling efficient carbon-carbon bond formation.

  • Pharmaceutical Intermediate: Essential for creating active pharmaceutical ingredients (APIs) requiring precise alkylation.
  • Peptide Synthesis: Used as a building block for constructing complex peptide sequences.
  • Organic Synthesis: Serves as a versatile reagent for introducing ester functionalities.
  • Research and Development: Widely used in laboratory settings for developing new chemical entities.

Synthesis and Quality Assurance

Our manufacturing process involves the controlled reaction of tert-butanol with bromoacetyl bromide under optimized conditions. This method ensures high conversion rates and minimizes the formation of impurities. Every batch undergoes rigorous testing using gas chromatography (GC) to verify purity levels meet or exceed the 98.0% threshold.

We understand the critical nature of supply chain reliability in the chemical industry. Therefore, we offer flexible packaging solutions, including standard 250 kg drums, with customization available to meet specific logistical requirements. Comprehensive documentation, including Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS), accompanies every shipment to ensure full regulatory compliance and safety during handling.