tert-Butylchlorodiphenylsilane
- CAS No.58479-61-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity tert-Butylchlorodiphenylsilane serves as a robust silylating agent for protecting hydroxyl groups in complex organic synthesis. Available in bulk quantities with full quality documentation.
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Product Overview
tert-Butylchlorodiphenylsilane is a premier organosilicon compound widely recognized for its exceptional utility in modern organic synthesis. As a specialized silylating agent, this reagent plays a critical role in the protection of hydroxyl functionalities during multi-step chemical transformations. Our manufacturing process ensures consistent high purity, making it an ideal choice for pharmaceutical intermediates and advanced material research.
The compound features a bulky tert-butyldiphenylsilyl group that provides significant steric hindrance. This characteristic offers superior stability against acidic and basic conditions compared to smaller silyl protecting groups. Consequently, it allows chemists to perform selective reactions on complex molecules without compromising sensitive functional groups elsewhere in the structure.
Technical Specifications
We adhere to strict quality control protocols to guarantee product performance. Each batch undergoes rigorous testing using gas chromatography and spectroscopic analysis. The following table outlines the key physical and chemical properties of our standard grade material.
| Parameter | Specification |
|---|---|
| CAS Number | 58479-61-1 |
| Molecular Formula | C16H19ClSi |
| Molecular Weight | 274.86 g/mol |
| Appearance | Colorless clear liquid |
| Purity (GC) | ≥98.5% |
| Density | 1.057 g/cm3 |
| Boiling Point | 90oC |
| Flash Point | 143oC |
| Refractive Index | 1.568 |
Industrial Applications
This silylating agent is extensively utilized in the synthesis of complex organic molecules. Its primary function involves the derivatization of alcohols, ketones, carboxylic acids, amines, amides, and mercaptans. By converting these functional groups into silyl ethers or esters, chemists can selectively manipulate specific sites within a molecule.
- Pharmaceutical Intermediate Synthesis: Protecting groups for steroid and macrolide synthesis.
- Agrochemical Development: Stabilizing reactive intermediates during pesticide formulation.
- Material Science: Surface modification and polymer end-capping applications.
- Research and Development: Essential reagent for total synthesis of natural products.
Quality Assurance And Storage
Quality is paramount in our production facility. We implement a comprehensive quality management system that tracks every stage from raw material sourcing to final packaging. Certificates of Analysis (COA) are provided with every shipment to verify compliance with stated specifications. Our laboratory equipment is calibrated regularly to ensure accurate measurement of purity and physical constants.
Proper storage is essential to maintain product integrity. The material should be kept in a cool, ventilated area away from direct sunlight and moisture sources. Containers must be tightly sealed to prevent hydrolysis, as chlorosilanes are sensitive to atmospheric humidity. Under recommended conditions, the product maintains its stability and performance characteristics for extended periods.
Why Partner With Us
As a global manufacturer with decades of experience, we offer competitive bulk pricing without compromising on quality. Our supply chain is optimized for reliability, ensuring timely delivery to laboratories and production facilities worldwide. We support custom packaging requirements to suit specific logistical needs. Our technical team is available to provide synthesis route guidance and safety data documentation. Choose us for a dependable supply of high-performance chemical intermediates.
