Intermediates

Tetrahydroxydiboron

  • CAS No.13675-18-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Tetrahydroxydiboron reagent ideal for Suzuki-Miyaura coupling and borylation reactions. Available in bulk with full documentation.

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Product Technical Details

Product Overview

Tetrahydroxydiboron, frequently recognized by its synonyms such as Hypodiboric acid or Diboronic Acid, stands as a critical inorganic reagent within the realm of modern organic synthesis. With the molecular formula B2H4O4 and a precise molecular weight of 89.65, this compound serves as a fundamental building block for introducing boron functionalities into complex organic frameworks. Our facility specializes in the production of this high-purity chemical, ensuring that every batch meets stringent international standards for pharmaceutical and agrochemical research.

The stability and reactivity profile of Tetrahydroxydiboron make it an indispensable tool for chemists engaged in cross-coupling reactions. Unlike many other boron sources, it offers a balanced combination of solubility and reactivity, allowing for smoother reaction kinetics under mild conditions. This characteristic is particularly valuable when synthesizing sensitive intermediates where harsh conditions could compromise the integrity of the molecular structure.

Key Specifications

Items of Analysis Standard of Analysis Test Results
Appearance White to off-white solid Conform
Assay ≥98.0% 99.9%
Density 1.435g/cm3 Conform
Refractive Index 1.397 Conform
Conclusion Conforms to Factory Standard

Industrial Applications

The primary utility of Tetrahydroxydiboron lies in its capacity to facilitate Suzuki-Miyaura coupling reactions, which are cornerstone processes in the construction of biaryl structures found in numerous active pharmaceutical ingredients. Beyond medicinal chemistry, this reagent is extensively utilized in the development of advanced materials and agrochemicals where precise boron incorporation is required.

  • Essential reagent for palladium-catalyzed cross-coupling reactions.
  • Used in the synthesis of boronic acids and esters for drug discovery.
  • Applied in the manufacturing of organic electronic materials.
  • Supports research into novel catalytic processes and mechanistic studies.

Quality Assurance and Handling

Quality control is paramount in our manufacturing process. Each production lot undergoes rigorous testing using advanced analytical techniques including HPLC and NMR spectroscopy to verify purity and structural integrity. We provide a comprehensive Certificate of Analysis (COA) with every shipment, ensuring transparency and reliability for our global partners.

Regarding handling, Tetrahydroxydiboron should be stored in a cool, dry environment away from moisture to maintain its stability. Proper packaging ensures that the product arrives in optimal condition, ready for immediate use in laboratory or industrial settings. Our logistics team is experienced in managing the safe transport of chemical reagents worldwide, adhering to all relevant safety regulations.