Intermediates

Tianeptine

  • CAS No.66981-73-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Tianeptine (CAS 66981-73-5), a tricyclic pharmaceutical intermediate used in advanced neurological therapeutics research and development.

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Product Technical Details

Product Overview

Tianeptine is a high-value tricyclic compound primarily utilized as a pharmaceutical intermediate in the development of advanced neurological therapeutics. With the molecular formula C21H25ClN2O4S and a molecular weight of 436.95 g/mol, it exhibits distinct pharmacological properties that differentiate it from classical tricyclic antidepressants. This product is supplied with stringent quality control to meet international standards for research and industrial-scale synthesis.

Specifications

Molecular FormulaC21H25ClN2O4S
Molecular Weight436.952 g/mol
Exact Mass436.122345
Melting Point129–131°C
Density1.4 ± 0.1 g/cm³
Boiling Point609.2 ± 65.0 °C at 760 mmHg
Flash Point322.2 ± 34.3 °C
LogP2.57
PSA95.09 Ų
Vapour Pressure0.0 ± 1.8 mmHg at 25°C
Refractive Index1.639

Quality Control

  • Assay: ≥99.0%
  • Residue on ignition: ≤0.20%
  • Loss on drying: ≤1.0%
  • Heavy metals: ≤20 ppm
  • Individual impurity: ≤0.1%
  • Total impurities: ≤0.5%

Industrial Applications

As a specialized intermediate, Tianeptine serves as a critical building block in the synthesis of complex pharmaceutical APIs targeting central nervous system disorders. Its unique mechanism—potentially involving modulation of glutamatergic pathways and neurotrophic factors—makes it a subject of interest in medicinal chemistry research. It is strictly intended for laboratory and industrial R&D use under compliant regulatory frameworks. This compound is not approved for direct human consumption in many jurisdictions, including the U.S., Canada, and the U.K.

Storage conditions require a cool, dry, and well-ventilated environment with the container tightly sealed to maintain stability and purity. Standard packaging is 25 kg per drum, with custom configurations available upon request.