Intermediates

Trifluoroacetophenone

  • CAS No.434-45-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity Trifluoroacetophenone (CAS 434-45-7) is a versatile fluorinated intermediate ideal for pharmaceutical and agrochemical synthesis.

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Product Technical Details

Product Overview

Trifluoroacetophenone, also known commercially as 2,2,2-Trifluoroacetophenone, is a highly valued fluorinated organic compound serving as a critical building block in modern chemical synthesis. Characterized by the presence of a trifluoromethyl group attached to a ketone structure, this reagent offers unique electronic and steric properties that enhance the biological activity and metabolic stability of downstream molecules. Our facility produces this compound under strict quality control standards to ensure consistency for demanding industrial applications.

As a key fluorinated intermediate, it plays an indispensable role in the development of advanced materials and fine chemicals. The incorporation of fluorine atoms into organic structures is a strategic approach in medicinal chemistry to improve lipophilicity and bioavailability. Consequently, reliable access to high-purity Trifluoroacetophenone is essential for research laboratories and production plants focused on innovation.

Key Specifications

We maintain rigorous testing protocols for every batch to guarantee compliance with international standards. The following table outlines the typical physical and chemical properties of our premium grade product.

ParameterSpecification
CAS Number434-45-7
Molecular FormulaC8H5F3O
Molecular Weight174.12 g/mol
AppearanceTransparent colorless to yellow liquid
Purity>98.0% (GC)
Density1.24 g/mL at 25 °C
Boiling Point165-166 °C
Refractive Indexn20/D 1.458
Flash Point107 °F
Water SolubilityPractically insoluble

Industrial Applications

The versatility of Trifluoroacetophenone makes it suitable for a wide array of synthetic pathways. In the pharmaceutical sector, it is frequently utilized as a precursor for synthesizing complex active pharmaceutical ingredients (APIs). The trifluoromethyl group enhances the binding affinity of drug candidates to target receptors, making this intermediate vital for neurological and oncological therapeutic development.

Beyond pharmaceuticals, this compound is extensively used in agrochemical research to develop next-generation pesticides and herbicides with improved environmental profiles. Additionally, it serves as a valuable reagent in the creation of new materials, including liquid crystals and polymers with enhanced thermal stability. Our comprehensive fluorochemical platform supports customers in scaling these applications from benchtop research to full-scale production.

Quality Assurance and Supply Chain

Our company is committed to establishing a complete fluorochemical products and technology platform to provide customers with convenient one-stop services. We manage the entire industrial chain from raw material procurement to final quality control. This vertical integration allows us to offer competitive bulk pricing without compromising on purity or safety.

  • Consistent supply chain management ensuring timely delivery.
  • Comprehensive documentation including Certificate of Analysis (COA).
  • Technical support for synthesis route optimization.
  • Secure storage and handling protocols for flammable materials.
  • Custom synthesis capabilities for specific project requirements.

Selecting the right partner for fluorinated intermediates is crucial for project success. We strive to build long-term relationships by providing reliable products and expert technical guidance. Whether you require standard specifications or customized solutions, our team is equipped to meet your specific manufacturing process needs with professionalism and integrity.