Intermediates

Trifluoromethanesulfonamide

  • CAS No.421-85-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Trifluoromethanesulfonamide (CAS 421-85-2) serves as a critical fluorinated building block for pharmaceutical and agrochemical synthesis.

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Product Technical Details

Product Overview

Trifluoromethanesulfonamide represents a cornerstone compound in modern organofluorine chemistry. As a stable and versatile sulfonamide derivative, this chemical plays a pivotal role in the construction of complex molecular architectures required for advanced material science and life science applications. Our facility produces this intermediate under strictly controlled conditions to ensure exceptional purity and consistency, meeting the rigorous demands of global research and industrial production teams.

The unique electronic properties imparted by the trifluoromethyl group make this substance an invaluable reagent for introducing fluorine into organic frameworks. Fluorination is a key strategy in medicinal chemistry to enhance metabolic stability and bioavailability of drug candidates. Consequently, reliable access to high-quality fluorinated building blocks is essential for accelerating development pipelines in both pharmaceutical and agrochemical sectors.

Technical Specifications

We maintain a robust quality control system to verify every batch against comprehensive physical and chemical standards. The following parameters represent our typical product specifications, ensuring compatibility with sensitive downstream synthesis reactions.

ParameterSpecification
CAS Number421-85-2
Molecular FormulaCHF3NO2S
Molecular Weight149.09 g/mol
Purity>98.0% (GC)
Melting Point120-124 °C
Boiling Point164.6 °C at 760 mmHg
Density1.73 g/cm3
AppearanceWhite to off-white powder

Industrial Applications

The utility of Trifluoromethanesulfonamide extends across multiple high-value industries. Its primary function serves as a precursor or protecting group in multi-step organic synthesis. Key application areas include:

  • Pharmaceutical Research: Used in the synthesis of novel therapeutic agents where fluorine substitution improves pharmacokinetic profiles.
  • Agrochemical Development: Employed in the creation of next-generation crop protection molecules with enhanced environmental stability.
  • Advanced Materials: Utilized in the production of specialized polymers and liquid crystals requiring specific electronic characteristics.
  • Chemical Synthesis: Acts as a versatile building block for creating more complex sulfonamide derivatives and triflimide precursors.

Quality Assurance and Safety

Our commitment to safety and quality is unwavering. Every shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. We adhere to international safety standards for the storage and handling of fluorinated compounds. Our logistics network ensures secure packaging to prevent moisture uptake or degradation during transit. Customers can rely on our technical support team for guidance on safe handling procedures and storage recommendations to maintain product integrity upon arrival.

Why Choose Our Manufacturing Platform

As a dedicated manufacturer with a complete fluorochemical technology platform, we offer more than just a product. We provide a partnership grounded in reliability and technical expertise. Our integrated supply chain allows for competitive bulk pricing without compromising on quality. Whether you require small quantities for laboratory research or large-scale volumes for industrial production, we have the capacity and flexibility to meet your needs. Contact our sales team today to discuss your specific requirements and request a quote for this premium fluorinated intermediate.