Intermediates

(Trifluoromethoxy)benzene

  • CAS No.456-55-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity (Trifluoromethoxy)benzene (CAS 456-55-3) designed for advanced organic synthesis applications. Available in bulk quantities with strict quality control.

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Product Technical Details

Product Overview

(Trifluoromethoxy)benzene is a specialized fluorinated aromatic compound widely recognized for its utility in modern organic synthesis and pharmaceutical development. As a key building block, this chemical introduces the trifluoromethoxy group into molecular structures, enhancing metabolic stability and lipophilicity. Our manufacturing process ensures consistent quality suitable for research and industrial scale production.

We operate as a compliant global manufacturer, providing this intermediate under strict quality assurance protocols. The compound is supplied as a colorless transparent liquid, ready for integration into complex synthetic routes requiring high precision and purity standards.

Key Specifications

Our production facility adheres to rigorous testing standards to guarantee performance. The following table outlines the critical physical and chemical parameters verified for each batch.

ParameterSpecification
CAS Number456-55-3
Molecular FormulaC7H5F3O
Molecular Weight162.109
AppearanceColorless transparent liquid
Assay≥98.0%
Density1.2±0.1 g/cm3
Boiling Point102.8±35.0 °C at 760 mmHg
Melting Point-50ºC
Flash Point12.2±0.0 °C

Industrial Applications

This fluorinated intermediate serves as a vital precursor in the synthesis of agrochemicals and pharmaceutical agents. The trifluoromethoxy moiety is particularly valued in medicinal chemistry for its ability to modulate electronic properties without significantly increasing steric hindrance. This makes it an ideal candidate for optimizing drug candidates during the lead optimization phase.

In addition to pharmaceutical uses, this compound is employed in the development of advanced materials and specialty chemicals. Researchers utilize it to explore structure-activity relationships where fluorine substitution is critical. Our bulk supply supports large-scale process chemistry, ensuring that production timelines are met without compromising on material quality.

Quality Assurance and Storage

Every shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with stated specifications. We maintain industrial purity levels through advanced distillation and purification techniques. Proper handling is essential to maintain product integrity during transport and storage.

  • Store in a cool, ventilated place away from direct sunlight.
  • Keep containers tightly closed when not in use.
  • Follow standard safety protocols for handling flammable liquids.
  • Available in 200 kg drums or customized packaging upon request.

For technical inquiries or bulk pricing details, our support team is ready to assist with synthesis route guidance and logistical coordination. We are committed to supplying reliable chemical intermediates to partners worldwide.