Intermediates

Triisopropylchlorosilane

  • CAS No.13154-24-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Triisopropylchlorosilane (CAS 13154-24-0) serves as a robust silylating agent for organic synthesis and resin production. Available in bulk drums with certified quality assurance.

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Product Technical Details

Product Overview

Triisopropylchlorosilane is a premier organosilicon compound widely recognized for its exceptional utility in advanced organic synthesis and industrial chemical manufacturing. As a highly effective silylating agent, this reagent introduces the triisopropylsilyl (TIPS) protecting group, offering superior steric hindrance compared to smaller silyl groups like trimethylsilyl. This unique structural characteristic ensures enhanced stability during complex multi-step synthetic routes, making it an indispensable tool for chemists working on pharmaceutical intermediates, specialized resins, and functional materials.

Our manufacturing process adheres to strict quality control standards, ensuring consistent batch-to-batch reliability. The product is supplied as a colorless transparent liquid with high chemical purity, suitable for sensitive reactions where moisture and impurity control are critical. By leveraging decades of expertise in silicone chemistry, we provide a reliable supply chain solution for global laboratories and production facilities.

Technical Specifications

ParameterSpecification
AppearanceColorless transparent liquid
Purity (Content)98% minimum
CAS Number13154-24-0
Packaging Options20Kg and 180Kg drums
Hazard ClassDangerous Goods Class 8

Industrial Applications

The versatility of Triisopropylchlorosilane extends across multiple high-value sectors. In the realm of organic synthesis, it is primarily employed to protect hydroxyl groups during the construction of complex molecules, including nucleoside intermediates and fine chemicals. Its bulky structure prevents unwanted side reactions, thereby improving overall yield and selectivity.

Furthermore, this chemical plays a pivotal role in the formulation of new marine antifouling coatings and high-performance resins. By modifying surface properties, it enhances the durability and weather resistance of polymeric materials. Key advantages for industrial users include:

  • Superior steric protection for sensitive functional groups.
  • Enhanced stability in harsh chemical environments.
  • Compatible with various synthesis routes and catalytic systems.
  • Ideal for scaling up from laboratory research to industrial production.

Storage and Safety Guidelines

To maintain optimal quality, Triisopropylchlorosilane must be stored in the original unopened container at temperatures of 25℃ or below. The product is sensitive to moisture and should be kept in a dry, well-ventilated area away from incompatible substances. The standard shelf life is one year from the date of production. Expired products should not be discarded immediately but can only be used after passing rigorous quality testing to ensure specifications are met.

Safety is paramount when handling this material. Classified as Dangerous Goods Class 8, it possesses corrosive properties. Personnel must utilize appropriate personal protective equipment (PPE), including chemical-resistant gloves and eye protection, during handling and transfer operations. We provide comprehensive Safety Data Sheets (SDS) and Certificates of Analysis (COA) with every shipment to ensure compliance with international transport and workplace safety regulations.