Intermediates

Triphenylacetic Acid

  • CAS No.595-91-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity triphenylacetic acid (98%) used as a salt-forming excipient in pharmaceutical development and organic synthesis.

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Product Technical Details

Product Overview

Triphenylacetic acid (CAS 595-91-5) is a specialized aromatic carboxylic acid widely employed in the pharmaceutical industry as a salt-forming excipient. With a molecular formula of C20H16O2 and a molecular weight of 288.34 g/mol, this compound exhibits high chemical stability under standard storage conditions and is valued for its role in modulating the physicochemical properties of active pharmaceutical ingredients (APIs), including vilanterol and related therapeutics.

Specifications

Molecular FormulaC20H16O2
Molecular Weight288.34 g/mol
Purity≥98%
AppearanceWhite to beige fine crystalline powder
Melting Point270–273 °C (lit.)
Boiling Point401.4 °C at 760 mmHg
Flash Point210.7 °C
StabilityStable under normal temperatures and pressures
Storage ConditionsStore in a cool, dry place. Keep container tightly closed when not in use.

Industrial Applications

As a key intermediate in advanced organic synthesis, triphenylacetic acid serves primarily as a counterion in the formation of stable, crystalline salts with basic drug molecules. This functionality enhances solubility, bioavailability, and shelf-life of final dosage forms. Its robust aromatic structure provides steric bulk that can influence crystal packing and polymorphism—critical factors in solid-state pharmaceutical development.

  • Used as a salt-forming agent for bronchodilators and other respiratory therapeutics
  • Serves as a building block in the synthesis of complex organic molecules
  • Compatible with standard API purification and isolation workflows
  • Meets stringent quality requirements for use in GMP-compliant manufacturing

Our triphenylacetic acid is manufactured under rigorous quality control protocols, ensuring batch-to-batch consistency and compliance with international regulatory standards for pharmaceutical intermediates.