Trityl Isothiocyanate
- CAS No.1726-94-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity Trityl Isothiocyanate (CAS 1726-94-9) designed for advanced organic synthesis and protecting group applications.
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Product Overview
Trityl Isothiocyanate, chemically known as Triphenylmethyl Isothiocyanate, is a specialized organic compound widely utilized in fine chemical synthesis and pharmaceutical research. With the CAS registry number 1726-94-9, this reagent serves as a critical building block for introducing the trityl protecting group onto nucleophilic centers, particularly amines and thiols. Our manufacturing process ensures exceptional chemical stability and consistency, making it an ideal choice for complex multi-step synthesis routes where protection and deprotection strategies are paramount.
As a leading global manufacturer, we understand the rigorous demands of modern medicinal chemistry. This product is synthesized under strict quality control protocols to minimize impurities that could interfere with downstream reactions. The trityl group is renowned for its acid-lability, allowing for selective deprotection under mild conditions, which is essential for preserving sensitive functional groups in advanced molecular structures.
Key Chemical Properties
The physical and chemical characteristics of Trityl Isothiocyanate are optimized for handling and reactivity in standard organic solvents. Its molecular structure, defined by the formula C20H15NS, provides a robust framework for various transformation reactions. The compound exhibits a distinct melting point range and thermal stability suitable for industrial-scale processing. Below are the detailed technical specifications verified by our quality assurance team.
| Parameter | Value |
|---|---|
| CAS Number | 1726-94-9 |
| Molecular Formula | C20H15NS |
| Molecular Weight | 301.41 g/mol |
| Appearance | White Powder |
| Purity (Assay) | ≥99.0% |
| Melting Point | 136-140 °C |
| Boiling Point | 410.7 °C at 760 mmHg |
| Density | 1.04 g/cm3 |
| Flash Point | 217 °C |
Industrial Applications
This isothiocyanate derivative is primarily employed as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialized polymers. Its primary function lies in organic synthesis where it acts as a protecting group reagent. The versatility of the trityl moiety allows chemists to safeguard reactive amines during harsh reaction conditions, ensuring high yields in the final product.
- Pharmaceutical Intermediate: Essential for constructing complex active pharmaceutical ingredients (APIs).
- Peptide Synthesis: Used to protect amino groups during solid-phase peptide synthesis.
- Fine Chemicals: Serves as a precursor for dyes, pigments, and functional materials.
- Research and Development: Widely used in academic and industrial labs for method development.
Quality Assurance and Packaging
We prioritize product integrity from synthesis to delivery. Each batch of Trityl Isothiocyanate undergoes comprehensive analytical testing, including HPLC and NMR spectroscopy, to confirm identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure compliance with your internal quality standards. Our standard packaging consists of 25 kg drums, designed to maintain product stability during transit. Custom packaging solutions are available upon request to suit specific logistical requirements.
Storage and Handling
To maintain optimal quality, store this material in a cool, ventilated area away from direct sunlight and moisture. The compound should be kept in tightly sealed containers to prevent hydrolysis or contamination. Proper personal protective equipment (PPE) is recommended during handling to ensure safety in accordance with standard laboratory safety protocols. For detailed safety data, please refer to the accompanying Safety Data Sheet (SDS).
