Intermediates

(Z)-Guggulsterone

  • CAS No.95975-55-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity (Z)-Guggulsterone (CAS 95975-55-6) is a premium plant sterol intermediate designed for nutraceutical research and chemical synthesis applications.

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Product Technical Details

Product Overview

(Z)-Guggulsterone is a highly specialized bioactive plant sterol derived from the gum resin of Commiphora wightii. As a critical chemical intermediate, it serves as a fundamental building block in the development of advanced nutraceutical formulations and pharmaceutical research projects. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for laboratories and industrial facilities requiring consistent quality and reliable performance in complex synthesis routes.

This compound is characterized by its specific stereochemistry, distinguished as the Z-isomer of Guggulsterone. It is widely recognized in the scientific community for its role as a farnesoid X receptor (FXR) antagonist. Our facility adheres to strict quality control protocols to guarantee that every batch meets rigorous international standards for chemical intermediates.

Technical Specifications

We maintain comprehensive analytical data for every production lot to ensure transparency and reliability. The following table outlines the key physical and chemical properties associated with this product.

ParameterSpecification
CAS Number95975-55-6
Molecular FormulaC21H28O2
Molecular Weight312.446
AppearanceWhite to off-white powder
Assay (Purity)≥99% (E+Z)
Z-Isomer Content50% - 65%
Loss on Drying≤0.5%
Residue on Ignition≤0.1%
Storage Condition2-8°C

Quality Assurance and Analysis

Quality is the cornerstone of our manufacturing philosophy. Each batch of (Z)-Guggulsterone undergoes extensive testing using high-performance liquid chromatography (HPLC) and other advanced analytical techniques. Our internal standards exceed typical industry requirements, ensuring minimal impurities and consistent isomer ratios. The certificate of analysis (COA) provided with every shipment details the specific test results, including heavy metal content, which is strictly controlled to remain below 10 ppm.

Our production facility is equipped with state-of-the-art technology to handle sensitive organic compounds. We implement robust safety measures during synthesis and packaging to maintain the integrity of the chemical structure. This commitment to quality allows our partners to proceed with their downstream applications with confidence, knowing that the raw material meets all specified criteria.

Applications and Usage

Primarily utilized as a research chemical and nutraceutical ingredient, (Z)-Guggulsterone is essential for studies involving lipid metabolism and cellular signaling pathways. It is frequently employed in the formulation of dietary supplements aimed at supporting healthy cholesterol levels and overall metabolic function. In industrial settings, it serves as a key intermediate for the synthesis of more complex steroidal derivatives.

Researchers value this compound for its specific biological activity profiles in cellular models. It is important to note that this product is intended for laboratory research and manufacturing use only. All handling should be conducted by qualified personnel equipped with appropriate safety gear. We support our clients with technical documentation to facilitate safe and effective integration into their respective processes.

Packaging and Storage

To preserve stability and potency, (Z)-Guggulsterone is packaged in secure, light-resistant containers. Standard packaging includes 25kg drums, though we offer customized solutions to meet specific logistical requirements. The product should be stored in a cool, dry, and well-ventilated area, ideally between 2-8°C. Containers must remain tightly closed when not in use to prevent exposure to moisture and air, which could affect the chemical stability over time.

We provide global shipping services with careful attention to regulatory compliance. Our logistics team ensures that all shipments are handled according to international safety standards for chemical transport. For bulk orders or specific formulation inquiries, our technical sales team is available to provide detailed support and customization options.