Intermediates

1-(2-Tetrahydrofuroyl)piperazine Hydrobromide

  • CAS No.63590-62-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in the synthesis of Terazosin Hydrochloride. Available in bulk with full COA support and competitive pricing.

Request Bulk Pricing

Product Technical Details

Product Overview

1-(2-Tetrahydrofuroyl)piperazine Hydrobromide is a specialized pharmaceutical intermediate characterized by its high chemical stability and precise molecular structure. As a piperazine derivative featuring a tetrahydrofuroyl group, this compound serves as a critical building block in the multi-step synthesis of advanced therapeutic agents. The hydrobromide salt form enhances the compound's stability during storage and handling, making it an ideal choice for large-scale industrial manufacturing processes where consistency is paramount.

Our manufacturing facility adheres to strict quality control protocols to ensure that every batch meets or exceeds the specified purity levels. This chemical is extensively utilized in the medicinal chemistry sector, particularly for researchers and production teams focused on developing alpha-adrenergic blocking agents. The robust physical properties, including a defined melting point range, facilitate reliable processing in various synthetic routes.

Technical Specifications

ParameterSpecification
Chemical Name1-(2-Tetrahydrofuroyl)piperazine Hydrobromide
CAS Number63590-62-5
Molecular FormulaC9H17BrN2O2
Molecular Weight265.15 g/mol
Purity≥98.0%
Melting Point103-107 °C
AppearanceWhite or off-white crystalline powder
Impurity Profile≤0.2%

Industrial Applications

The primary application of this intermediate lies in the synthesis of Terazosin Hydrochloride, a well-known pharmaceutical agent used in the management of hypertension and benign prostatic hyperplasia. The high purity grade ensures that downstream reactions proceed with minimal side products, thereby optimizing the overall yield of the final active pharmaceutical ingredient (API). Impurities are strictly controlled to prevent complications in subsequent purification steps.

Beyond its role in Terazosin production, this piperazine derivative is valuable for custom synthesis projects requiring specific acylating agents. Pharmaceutical developers utilize this compound to explore structure-activity relationships in new drug candidates. Our supply chain is optimized to support both pilot-scale research and commercial-scale production, ensuring timely delivery regardless of project scope.

Quality Assurance and Storage

Quality is the cornerstone of our chemical manufacturing operations. Each production batch undergoes rigorous testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all critical quality attributes.

  • Store in a cool, dry, and well-ventilated area away from direct sunlight.
  • Keep containers tightly closed to prevent moisture absorption due to the hygroscopic nature of the hydrobromide salt.
  • Avoid exposure to strong heat sources or incompatible oxidizing agents.
  • Standard packaging includes 25kg cardboard drums, with custom packaging available upon request.

By choosing our 1-(2-Tetrahydrofuroyl)piperazine Hydrobromide, partners gain access to a reliable supply of high-quality intermediates backed by decades of industry expertise. We are committed to supporting global pharmaceutical innovation through consistent product performance and responsive customer service.