1-Bromo-2-fluoro-4-iodobenzene
- CAS No.136434-77-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1-bromo-2-fluoro-4-iodobenzene (CAS 136434-77-0), a key halogenated aromatic intermediate for advanced OLED and liquid crystal material synthesis.
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Product Overview
1-Bromo-2-fluoro-4-iodobenzene is a highly versatile, multi-halogenated aromatic compound widely employed as a critical building block in the synthesis of advanced functional materials. With its unique combination of bromo, fluoro, and iodo substituents at strategic positions on the benzene ring, this intermediate offers exceptional regioselectivity for cross-coupling reactions such as Suzuki, Stille, and Sonogashira protocols. Its precise halogen pattern enables sequential functionalization, making it indispensable in the development of high-performance organic electronic components.
Specifications
| Molecular Formula | C6H3BrFI |
|---|---|
| Molecular Weight | 300.895 g/mol |
| CAS Number | 136434-77-0 |
| Appearance | White or light yellow crystal |
| Purity | >99.5% |
| Density | 2.281 g/cm³ |
| Boiling Point | 80 °C at 2.5 mmHg |
| Melting Point | 34–38 °C (lit.) |
| Refractive Index | 1.628 |
| Flash Point | >230 °F |
Industrial Applications
This compound serves primarily as a specialized intermediate in the production of liquid crystal monomers and emissive layers for OLED (organic light-emitting diode) technologies. Its tailored halogen array facilitates the construction of complex π-conjugated systems required for efficient charge transport and luminescence in next-generation displays and lighting solutions. Additionally, it finds utility in pharmaceutical research as a scaffold for synthesizing structurally diverse bioactive molecules through modern C–H activation and metal-catalyzed coupling methodologies.
Key advantages include:
- High regiochemical control for sequential derivatization
- Excellent compatibility with palladium-catalyzed transformations
- Rigorous quality assurance with batch-specific Certificates of Analysis (COA)
- Scalable supply for industrial R&D and pilot-scale manufacturing
Stored under inert, dry conditions in sealed containers, 1-bromo-2-fluoro-4-iodobenzene maintains stability during extended shelf life. Packaging is typically provided in 20 kg fiber drums, with custom options available to meet specific logistical or safety requirements.
