Intermediates

1-(Bromomethyl)-2-(Trifluoromethyl)Benzene

  • CAS No.395-44-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 1-(Bromomethyl)-2-(Trifluoromethyl)Benzene intermediate for advanced organic synthesis. High purity ≥99.0% with global supply availability.

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Product Technical Details

Product Overview

1-(Bromomethyl)-2-(Trifluoromethyl)Benzene is a highly specialized fluorinated organic intermediate designed for complex pharmaceutical and agrochemical synthesis pathways. As a key building block containing both bromine and trifluoromethyl functional groups, this compound offers exceptional reactivity for nucleophilic substitution reactions. Our manufacturing process ensures consistent molecular integrity, making it an ideal choice for research laboratories and industrial production scales requiring precise chemical structures.

The presence of the trifluoromethyl group significantly enhances the lipophilicity and metabolic stability of downstream molecules, which is critical in modern drug design. This chemical is produced under strict quality control protocols to guarantee minimal impurities, ensuring reliable performance in sensitive synthetic routes. We prioritize safety and compliance throughout the production lifecycle, adhering to international chemical safety standards.

Technical Specifications

ParameterValue
CAS Number395-44-8
Molecular FormulaC8H6BrF3
Molecular Weight239.03 g/mol
Purity (GC)≥99.0%
AppearanceWhite powder
Density1.571 g/cm³
Melting Point34-35°C
Boiling Point72°C
Flash Point83°C
Refractive Index1.496-1.499

Industrial Applications

This fluorinated benzyl bromide derivative serves as a versatile precursor in the synthesis of biologically active compounds. It is extensively utilized in the development of novel pharmaceutical APIs, particularly where fluorine substitution is required to improve bioavailability. The bromomethyl group facilitates easy coupling with various nucleophiles, enabling the construction of complex molecular architectures efficiently.

Beyond pharmaceuticals, this intermediate finds application in the agrochemical sector for creating robust pesticides and herbicides. The chemical stability provided by the trifluoromethyl moiety ensures longevity and effectiveness in field conditions. Researchers also employ this compound in material science for developing specialized polymers and liquid crystals where specific electronic properties are needed. Our technical team supports customers with synthesis route optimization to maximize yield and minimize waste.

Quality Assurance And Packaging

  • Each batch undergoes rigorous Gas Chromatography (GC) analysis to verify purity levels exceed 99.0%.
  • Comprehensive Certificate of Analysis (COA) is provided with every shipment for traceability.
  • Packaged in 25 kg drums with inner lining to prevent moisture absorption and contamination.
  • Custom packaging solutions are available upon request to meet specific logistical requirements.
  • Storage recommendations include keeping the container tightly closed in a cool, ventilated area away from direct sunlight.
  • Handling procedures should follow standard safety protocols for halogenated organic compounds, including appropriate PPE usage.

We are committed to delivering high-quality chemical intermediates with reliable lead times. Our global logistics network ensures timely delivery while maintaining product integrity during transit. For large-scale procurement or custom synthesis inquiries, our sales team is ready to provide competitive bulk pricing and detailed technical documentation.