1-Carboxy-1-methylethoxyammonium Chloride
- CAS No.89766-91-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1-Carboxy-1-methylethoxyammonium chloride (CAS 89766-91-6), a key intermediate for synthesizing advanced beta-lactam antibiotics such as ceftazidime and aztreonam.
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Product Overview
1-Carboxy-1-methylethoxyammonium chloride is a high-value pharmaceutical intermediate widely employed in the synthesis of third-generation cephalosporins and monobactam antibiotics. With a molecular formula of C4H10ClNO3 and a molecular weight of 155.58 g/mol, this compound serves as a critical building block in complex organic synthesis pathways targeting anti-infective therapeutics.
Specifications
| Molecular Formula | C4H10ClNO3 |
|---|---|
| Molecular Weight | 155.58 g/mol |
| CAS Number | 89766-91-6 |
| Appearance | Off-white solid |
| Purity | ≥98.0% |
| Melting Point | 156–165°C |
| Boiling Point | 264.1°C |
| Density | 1.199 g/cm³ |
| Refractive Index | 1.463 |
| Flash Point | 113.5°C |
Industrial Applications
This compound is primarily utilized as a specialized synthon in the industrial-scale production of beta-lactam antibiotics, notably ceftazidime and aztreonam. Its unique aminooxy functional group enables selective oxime formation, facilitating efficient side-chain introduction during antibiotic core modification. As a non-final active pharmaceutical ingredient (API), it plays an essential role in multi-step GMP-compliant manufacturing processes within regulated pharmaceutical environments.
- Enables precise structural derivatization in cephalosporin synthesis
- Compatible with standard aqueous and organic reaction media
- Supplied in high industrial purity to minimize downstream purification burden
- Stable under recommended storage conditions for extended shelf life
Stored in a cool, well-ventilated area away from moisture and incompatible materials, this intermediate is typically packed in 25 kg fiber drums or customized packaging per client specifications. All batches are accompanied by comprehensive Certificates of Analysis (COA) to ensure traceability and compliance with international quality standards.
