Intermediates

(1-Ethylpyrrolidin-2-yl)methanamine

  • CAS No.26116-12-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

A high-purity liquid pharmaceutical intermediate used primarily in the synthesis of advanced therapeutic agents. Available in bulk quantities with full quality documentation.

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Product Technical Details

Product Overview

(1-Ethylpyrrolidin-2-yl)methanamine is a sophisticated organic compound characterized by its pyrrolidine ring structure substituted with an ethyl group and an aminomethyl functionality. This chemical serves as a critical building block in the realm of medicinal chemistry and fine chemical synthesis. As a versatile intermediate, it provides the necessary structural framework for constructing more complex molecular architectures required in modern pharmaceutical development. Our facility produces this compound under strict quality control standards to ensure consistency and reliability for downstream synthesis processes.

The compound is recognized for its stability and reactivity profile, making it an ideal candidate for various nucleophilic substitution reactions. In the context of large-scale manufacturing, maintaining high purity is essential to prevent side reactions that could compromise the yield of the final active pharmaceutical ingredient. We utilize advanced distillation and purification techniques to achieve assay levels that meet or exceed industry standards for research and production-grade materials.

Technical Specifications

Understanding the physical and chemical properties of this intermediate is vital for process engineers and chemists planning synthesis routes. The following table outlines the key parameters verified during our quality assurance testing protocols. Each batch is analyzed to confirm compliance with these specifications before release.

ParameterSpecification
CAS Number26116-12-1
Molecular FormulaC7H16N2
Molecular Weight128.215 g/mol
AppearanceColorless to light-yellow liquid
Assay≥99.0%
Density0.9±0.1 g/cm3
Boiling Point161.9±0.0 °C at 760 mmHg
Flash Point60.6±0.0 °C
Moisture Content≤2.0%
Single Impurity≤0.5%
Total Impurities≤1.0%

Industrial Applications

This pyrrolidine derivative is predominantly utilized in the pharmaceutical sector as a key precursor for the synthesis of specialized therapeutic agents. It plays a significant role in the manufacturing pipeline for neurological therapeutics, including specific antipsychotic medications such as Amisulpride. The structural integrity of the aminomethyl group allows for efficient coupling reactions, facilitating the formation of amide or amine bonds required in the final drug substance.

Beyond pharmaceuticals, this intermediate finds utility in the development of agrochemicals and fine chemicals where pyrrolidine motifs are required. Researchers value this material for its predictable reactivity and compatibility with various catalytic systems. Whether used in early-stage drug discovery or late-stage commercial production, the consistency of the raw material directly impacts the efficiency and safety of the overall synthesis route.

Quality Assurance and Handling

Safety and quality are paramount in our manufacturing operations. Given the flash point of approximately 60.6 degrees Celsius, appropriate safety measures must be implemented during storage and handling. We recommend storing the product in a cool, ventilated area away from incompatible substances such as strong oxidizing agents. All containers are sealed to prevent moisture absorption, which could affect the assay purity over time.

Our quality control laboratory employs high-performance liquid chromatography (HPLC) and gas chromatography (GC) to verify purity levels and impurity profiles. Every shipment is accompanied by a Certificate of Analysis (COA) detailing the test results for that specific batch. This transparency ensures that our partners have full traceability and confidence in the material they receive for their production lines.

Why Partner With Us

  • Consistent supply chain with scalable production capacity for bulk orders.
  • Rigorous quality testing ensuring high industrial purity standards.
  • Competitive pricing structures for long-term manufacturing partnerships.
  • Comprehensive technical support and documentation including COA and MSDS.
  • Global logistics capabilities ensuring timely delivery to international facilities.