1,1,1,2,2-Pentafluoro-4-iodobutane

Product Overview

1,1,1,2,2-Pentafluoro-4-iodobutane (CAS 40723-80-6) is a versatile fluorinated alkyl iodide widely employed as a specialty intermediate in advanced organic synthesis. This compound serves as a critical building block in the development of novel fluorine-containing molecules, particularly within pharmaceutical research, agrochemical innovation, and advanced materials science. Its unique combination of a perfluorinated segment and a reactive iodine terminus enables selective C–C and C–heteroatom bond formations under controlled conditions.

Specifications

Industrial Applications

As a key fluorochemical intermediate, 1,1,1,2,2-pentafluoro-4-iodobutane is integral to modern synthetic strategies requiring precise fluorine incorporation. Its applications include:

• Serving as a precursor in the synthesis of complex pharmaceutical APIs and neurological therapeutics where metabolic stability and lipophilicity are enhanced by fluorine substitution.
• Enabling the construction of fluorinated side chains in next-generation agrochemicals with improved environmental persistence profiles.
• Acting as a reagent or substrate in cross-coupling reactions (e.g., Kumada, Negishi, or Suzuki-type transformations) for the generation of structurally diverse fluorinated scaffolds.
• Supporting the development of specialty polymers and electronic materials that demand high thermal and chemical resistance.

Manufacturers leverage this compound within tightly controlled fluorochemical platforms to ensure batch-to-batch consistency, regulatory compliance, and scalability from lab to pilot plant.