Intermediates

2-(N-Boc-N-methylamino)ethanol

  • CAS No.57561-39-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade pharmaceutical intermediate used in oncology research synthesis. High purity ≥98% with strict quality control.

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Product Technical Details

Product Overview

2-(N-Boc-N-methylamino)ethanol represents a critical building block in modern medicinal chemistry and pharmaceutical process development. As a protected amino alcohol derivative, this compound features a tert-butoxycarbonyl (Boc) group that provides essential stability during multi-step organic synthesis. Our facility specializes in the large-scale production of this high-value intermediate, ensuring consistent quality for research institutions and pharmaceutical manufacturers worldwide.

The chemical structure combines a methylated amine with a hydroxyethyl chain, protected by the acid-labile Boc group. This configuration allows chemists to selectively manipulate the hydroxyl functionality while preserving the amine integrity, or vice versa, depending on the synthetic route required. Such versatility makes it an indispensable reagent in the construction of complex small molecule therapies.

Technical Specifications

ParameterSpecification
Chemical Name2-(N-Boc-N-methylamino)ethanol
CAS Registry Number57561-39-4
Molecular FormulaC8H17NO3
Molecular Weight175.23 g/mol
AppearanceClear light yellow liquid
Purity (HPLC)≥98.0%
Density1.037 g/cm³
Boiling Point120-126°C at 4mmHg
Refractive Index1.458

Industrial Applications

This compound serves as a key substituent in the synthesis of advanced pharmaceutical agents, including signal transducer and activator of transcription 3 (STAT3) inhibitors. In oncology research, STAT3 inhibitors are investigated for their potential to disrupt cancer cell signaling pathways. Our product provides the necessary chemical foundation for constructing these bioactive molecules with high precision.

Beyond oncology, N-Boc-N-methylethanolamine is utilized in various organic synthesis applications where protected amino alcohols are required. The Boc protecting group is particularly favored due to its stability under basic conditions and its clean removal under acidic conditions, facilitating efficient workflow in process chemistry. Researchers value this intermediate for its reliability in forming carbamates and its compatibility with diverse reaction conditions.

Quality Assurance and Storage

We adhere to stringent quality management systems to guarantee the integrity of every batch. Each production lot undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to confirm identity and purity levels. A Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with international standards.

  • Packaging: Standard 25 kg drums, with custom packaging available upon request.
  • Storage Conditions: Store at 2-8°C in a tightly closed container.
  • Handling: Keep in a cool, dry place away from direct sunlight and moisture.
  • Stability: Stable under recommended storage conditions for extended periods.

Our global supply chain ensures timely delivery to laboratories and manufacturing sites across continents. For bulk inquiries or technical support regarding synthesis routes, our team of experienced chemists is ready to assist.