2',3',5'-Tri-O-acetyluridine
- CAS No.13189-00-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity pharmaceutical intermediate used extensively in antiviral synthesis and nucleoside analog research.
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Product Overview
2',3',5'-Tri-O-acetyluridine is a critically important protected nucleoside derivative utilized extensively within the pharmaceutical and biotechnology sectors. As a fully acetylated form of uridine, this compound serves as a versatile building block for the synthesis of complex nucleoside analogs and antiviral active pharmaceutical ingredients. The presence of acetyl protecting groups at the 2', 3', and 5' positions enhances the stability of the sugar moiety during various chemical transformations, making it an indispensable reagent in modern organic synthesis.
Our manufacturing process ensures that every batch meets rigorous international standards for purity and consistency. This chemical is particularly valued in the development of therapeutic agents targeting viral infections, where precise stereochemistry and high chemical integrity are paramount for downstream efficacy and safety profiles.
Key Specifications
We maintain strict quality control protocols to guarantee that the physical and chemical properties align with established pharmacopeial expectations. The following table outlines the standard analytical parameters verified during our production cycle.
| Items of Analysis | Standard of Analysis | Test Results |
|---|---|---|
| Appearance | White or almost white crystalline powder | Conform |
| Loss on drying | ≤1.0% | 0.02% |
| Residue on ignition | ≤0.2% | 0.06% |
| Heavy Metals | ≤20 ppm | Conform |
| Purity | ≥98% | 99.0% |
| Conclusion | Conforms to Factory Standard | |
Industrial Applications
The primary utility of this compound lies in its role as a precursor for nucleoside-based drugs. Researchers and process chemists utilize this intermediate to construct modified nucleosides that exhibit enhanced bioavailability or specific antiviral activity. Key application areas include:
- Synthesis of antiviral pharmaceutical intermediates for hepatitis and influenza treatments.
- Development of oligonucleotide therapeutics and diagnostic probes.
- Chemical modification studies aimed at improving metabolic stability of nucleoside analogs.
- Academic and industrial research into novel RNA-based technologies.
Storage and Handling
To maintain optimal chemical stability and prevent degradation of the acetyl groups, proper storage conditions are essential. The material should be kept in a tightly sealed container under inert atmosphere when possible. Long-term storage is recommended at low temperatures to minimize hydrolysis risks. Always handle with appropriate personal protective equipment in a well-ventilated laboratory environment. Certificates of Analysis are provided with every shipment to verify batch-specific quality metrics.
