2,7-Dibromo-9,9-difluoro-9H-fluorene
- CAS No.1229603-71-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used in antiviral drug synthesis. Available in bulk quantities with comprehensive quality documentation.
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Product Overview
2,7-Dibromo-9,9-difluoro-9H-fluorene is a highly specialized fluorinated organic compound designed for advanced pharmaceutical synthesis. This molecule features a robust fluorene backbone substituted with bromine atoms at the 2 and 7 positions and fluorine atoms at the 9 position. Such structural configuration provides exceptional stability and reactivity, making it an invaluable building block in the construction of complex therapeutic agents. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and production environments.
The introduction of fluorine atoms into organic molecules is a critical strategy in modern medicinal chemistry. Fluorine substitution often enhances metabolic stability, lipophilicity, and bioavailability of the final drug product. Consequently, this intermediate plays a pivotal role in the development of next-generation antiviral medications and other small molecule therapeutics. We adhere to strict quality control protocols to guarantee that every batch meets international standards for pharmaceutical intermediates.
Chemical Properties and Specifications
Understanding the physicochemical properties of this compound is essential for safe handling and effective utilization in synthesis routes. The presence of bromine allows for versatile cross-coupling reactions, while the difluoro substitution modulates the electronic properties of the aromatic system. Below are the detailed technical specifications verified through our internal quality assurance laboratories.
| Parameter | Value |
|---|---|
| Chemical Name | 2,7-Dibromo-9,9-difluoro-9H-fluorene |
| CAS Number | 1229603-71-7 |
| Molecular Formula | C13H6Br2F2 |
| Molecular Weight | 359.99 g/mol |
| Purity (Assay) | ≥98.0% |
| Density | 2.1 g/cm3 |
| Boiling Point | 361.5 °C |
| Flash Point | 172.5 °C |
| Refractive Index | 1.683 |
Industrial Applications
This compound serves primarily as a key intermediate in the synthesis of sophisticated pharmaceutical agents. It is notably utilized in the production pathways of antiviral drugs, including specific inhibitors used in the treatment of chronic viral infections. The high purity grade we supply ensures minimal impurity carryover into subsequent synthesis steps, which is critical for regulatory compliance in drug manufacturing.
- Pharmaceutical API Synthesis: Essential building block for complex small molecule drugs.
- Antiviral Research: Used in the development of treatments for hepatitis and other viral conditions.
- Organic Chemistry: Valuable reagent for cross-coupling reactions such as Suzuki or Buchwald couplings.
- Material Science: Potential application in the development of fluorinated organic materials.
Quality Assurance and Packaging
As a global manufacturer, we prioritize product integrity from synthesis to delivery. Each production batch undergoes rigorous testing using advanced analytical techniques including HPLC and NMR to confirm identity and purity. A Certificate of Analysis (COA) is provided with every shipment to document compliance with specified parameters. Our facility operates under strict safety and environmental guidelines to ensure sustainable production practices.
Standard packaging consists of 25 kg drums lined with protective materials to prevent moisture ingress and contamination. However, we understand that different clients have varying logistical requirements. Therefore, we offer flexible packaging solutions tailored to customer needs, ensuring safe transport via air, sea, or land freight. Proper storage in a cool, ventilated area away from incompatible substances is recommended to maintain product stability over time.
