2-Amino-5-bromothiazole Monohydrobromide
- CAS No.61296-22-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Amino-5-bromothiazole monohydrobromide (CAS 61296-22-8), a key halogenated heterocyclic intermediate for advanced pharmaceutical and agrochemical synthesis.
Request Bulk PricingProduct Technical Details
Product Overview
2-Amino-5-bromothiazole monohydrobromide is a halogenated thiazole derivative widely employed as a critical building block in the synthesis of complex pharmaceutical active ingredients and specialty agrochemicals. With its reactive bromo and amino functionalities on a rigid thiazole scaffold, this compound enables selective cross-coupling and nucleophilic substitution reactions, making it indispensable in modern medicinal chemistry workflows.
Specifications
| Molecular Formula | C₃H₄Br₂N₂S |
|---|---|
| Molecular Weight | 259.95 g/mol |
| Appearance | Light yellow to light brown crystalline powder |
| Melting Point | 165 °C (dec.) |
| Boiling Point | 192.5 °C at 760 mmHg |
| Flash Point | 70.2 °C |
| Purity (HPLC) | ≥96.0% (Typical: 96.7%) |
Industrial Applications
This high-purity intermediate is primarily utilized in the development of novel therapeutic agents targeting metabolic and inflammatory pathways. Its structural motif serves as a versatile precursor in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed transformations. Additionally, it finds application in the synthesis of fungicides and herbicides requiring halogenated nitrogen heterocycles for optimal bioactivity.
- Enables regioselective functionalization via bromine displacement
- Compatible with standard peptide and small-molecule coupling protocols
- Supplied with full analytical documentation including COA and HPLC chromatograms
- Manufactured under ISO-compliant quality systems for consistent batch-to-batch performance
