2-Bromo-3,4-difluoroaniline
- CAS No.1092349-87-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Bromo-3,4-difluoroaniline intermediate for pharmaceutical synthesis. Available in bulk quantities with full quality documentation.
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Product Overview
2-Bromo-3,4-difluoroaniline represents a critical fluorinated building block within the realm of advanced organic synthesis. As a specialized aromatic amine derivative, this compound is extensively utilized in the development of complex pharmaceutical agents and agrochemical formulations. The strategic incorporation of fluorine atoms into the benzene ring structure enhances metabolic stability and bioavailability, making this intermediate highly valuable for medicinal chemistry applications.
Our manufacturing process ensures consistent quality and high purity levels, adhering to strict international standards for chemical intermediates. We understand the precise requirements of research and development teams who rely on reliable sourcing for their synthesis pathways. This product serves as a foundational element for constructing more elaborate molecular architectures required in modern therapeutic discovery.
Technical Specifications
The following table outlines the key physical and chemical properties verified through our quality control laboratories. Each batch is tested to ensure compliance with the specified parameters before release.
| Parameter | Specification |
|---|---|
| CAS Number | 1092349-87-5 |
| Molecular Formula | C6H4BrF2N |
| Molecular Weight | 208.00 g/mol |
| Appearance | Solid |
| Purity | ≥98.0% |
| Density | 1.8±0.1 g/cm3 |
| Boiling Point | 236.4±35.0 °C at 760 mmHg |
| Flash Point | 96.8±25.9 °C |
| Refractive Index | 1.570 |
Industrial Applications
This fluorinated aniline derivative is primarily employed as a key intermediate in the pharmaceutical industry. It facilitates the synthesis of various biologically active compounds where the presence of halogen substituents is crucial for receptor binding affinity. The bromo and fluoro substituents provide versatile handles for further functionalization through cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations.
Beyond pharmaceuticals, this chemical finds utility in the production of specialized polymers and liquid crystals where thermal stability and specific electronic properties are required. Researchers utilize this building block to explore structure-activity relationships in novel drug candidates, leveraging the unique electronic effects imparted by the fluorine atoms.
Quality Assurance and Packaging
We maintain a robust quality management system to guarantee the integrity of every shipment. Comprehensive documentation, including Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS), accompanies each order. Our packaging solutions are designed to preserve product stability during transit and storage.
- Standard Packaging: 25kg drums lined with protective materials.
- Custom Packaging: Available upon request for specific logistical requirements.
- Quality Testing: Every batch undergoes rigorous HPLC and NMR analysis.
- Traceability: Full batch tracking from synthesis to delivery.
Storage and Handling
To maintain optimal quality, 2-Bromo-3,4-difluoroaniline should be stored in a tightly closed container within a cool, dry, and well-ventilated area. It is essential to keep the material away from incompatible substances such as strong oxidizing agents. Personnel handling this chemical should adhere to standard safety protocols, including the use of appropriate personal protective equipment to prevent inhalation or skin contact. Proper storage conditions ensure the longevity and performance of the product in your synthesis workflows.
