Intermediates

2-Bromo-3-fluorobenzoic acid

  • CAS No.132715-69-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-3-fluorobenzoic acid designed for advanced organic synthesis. Reliable supply with comprehensive quality documentation.

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Product Technical Details

Product Overview

2-Bromo-3-fluorobenzoic acid is a specialized halogenated aromatic compound serving as a critical building block in modern organic synthesis. Characterized by the presence of both bromine and fluorine substituents on the benzoic acid backbone, this molecule offers unique reactivity profiles essential for complex chemical transformations. Our facility produces this compound under strict quality control standards to ensure consistency for research and industrial applications.

The strategic positioning of the halogen atoms allows for selective functionalization, making it a preferred choice for medicinal chemists and process development teams. As a verified intermediate, it supports the creation of high-value pharmaceuticals and agrochemicals through robust coupling reactions.

Technical Specifications

We adhere to rigorous analytical protocols to guarantee product integrity. Each batch undergoes comprehensive testing using HPLC and NMR spectroscopy to confirm identity and purity levels. The following table outlines the key physical and chemical properties associated with this material:

ParameterValue
CAS Number132715-69-6
Molecular FormulaC7H4BrFO2
Molecular Weight219.008
AppearanceWhite to off-white powder
Assay≥98.0%
Melting Point158-160°C
Density1.8±0.1 g/cm3
Boiling Point292.7±25.0 °C at 760 mmHg
Flash Point130.8±23.2 °C

Industrial Applications

This fluorinated benzoic acid derivative is primarily utilized in the synthesis of complex organic molecules. Its dual halogen structure facilitates versatile reaction pathways, including:

  • Cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig aminations.
  • Nucleophilic aromatic substitution processes leveraging the fluorine substituent.
  • Construction of biaryl structures common in active pharmaceutical ingredients.
  • Development of novel ligands and catalysts for homogeneous catalysis.

Researchers value this intermediate for its stability and solubility profile, which streamlines downstream processing in multi-step synthesis routes.

Quality Assurance and Packaging

Quality is paramount in our manufacturing process. We provide a Certificate of Analysis (COA) with every shipment, detailing batch-specific test results. Our packaging solutions are designed to maintain product stability during transit and storage.

Standard packaging includes 25 kg drums, though we accommodate custom requirements based on volume needs. All containers are sealed to prevent moisture ingress and contamination. We recommend storing the material in a cool, ventilated area away from incompatible substances to preserve its chemical properties over time.

Safety and Handling

While this compound is intended for professional industrial use, standard safety precautions apply. Personnel should utilize appropriate personal protective equipment (PPE), including gloves and eye protection, during handling. Ensure adequate ventilation in the workspace to minimize exposure to dust or vapors. In case of spillage, follow standard chemical containment procedures as outlined in the Safety Data Sheet (SDS).