2-Bromo-3-methylbenzoic acid
- CAS No.53663-39-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Bromo-3-methylbenzoic acid (CAS 53663-39-1) designed for advanced organic synthesis. Reliable supply with comprehensive COA.
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Product Overview
2-Bromo-3-methylbenzoic acid is a highly specialized organic intermediate that plays a pivotal role in the synthesis of complex pharmaceutical compounds and agrochemical agents. As a substituted benzoic acid derivative, this compound features a bromine atom at the ortho position and a methyl group at the meta position relative to the carboxylic acid functionality. This specific substitution pattern provides unique reactivity profiles, making it an indispensable building block for cross-coupling reactions and heterocyclic synthesis.
Our manufacturing facility produces this chemical under strict quality control protocols to ensure consistent batch-to-batch reliability. We understand that downstream synthesis processes require raw materials with defined purity levels to minimize side reactions and maximize yield. Therefore, our production line is optimized to deliver material that meets rigorous international standards for organic synthesis intermediates.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-Bromo-3-methylbenzoic acid |
| CAS Number | 53663-39-1 |
| Molecular Formula | C8H7BrO2 |
| Molecular Weight | 215.044 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 135-138 °C |
| Boiling Point | 308.3±30.0 °C at 760 mmHg |
| Density | 1.6±0.1 g/cm3 |
| Flash Point | 140.2±24.6 °C |
Industrial Applications
This brominated benzoic acid derivative is primarily utilized in the pharmaceutical industry for the construction of biologically active molecules. The presence of the bromine atom allows for versatile functionalization through palladium-catalyzed coupling reactions such as Suzuki, Heck, or Sonogashira couplings. Additionally, the carboxylic acid group offers opportunities for amidation or esterification, enabling chemists to introduce diverse structural motifs into target molecules.
- Pharmaceutical Intermediate: Used in the synthesis of kinase inhibitors and anti-inflammatory agents.
- Agrochemical Synthesis: Serves as a precursor for herbicides and fungicides requiring aromatic scaffolds.
- Material Science: Employed in the development of organic ligands for catalysis and polymer modification.
- Research and Development: Essential reagent for academic and industrial organic chemistry laboratories.
Quality Assurance and Safety
We prioritize safety and quality in every step of our supply chain. Each batch of 2-Bromo-3-methylbenzoic acid undergoes comprehensive analytical testing, including HPLC, GC, and NMR spectroscopy, to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure transparency and compliance with your internal quality standards.
Regarding storage, this product should be kept in a cool, ventilated area away from direct sunlight and moisture. Proper packaging in 25 kg drums or customized containers ensures stability during transit. Our logistics team is experienced in handling chemical shipments globally, ensuring timely delivery while adhering to all relevant transportation regulations. For large-scale requirements, we offer flexible packaging solutions and technical support to assist with integration into your manufacturing process.
