Intermediates

2-Chloro-5-fluoro-4-iodopyridine

  • CAS No.884494-49-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-Chloro-5-fluoro-4-iodopyridine designed for advanced organic synthesis and pharmaceutical research applications with reliable supply chain support.

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Product Technical Details

Product Overview

2-Chloro-5-fluoro-4-iodopyridine is a highly specialized halogenated pyridine derivative engineered for precision organic synthesis. As a critical building block in modern medicinal chemistry, this compound facilitates complex molecular constructions required for developing advanced pharmaceutical agents. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for research and development teams focused on kinase inhibitors and other therapeutic candidates.

We understand the rigorous demands of pharmaceutical supply chains. Therefore, every production run undergoes strict quality control protocols to meet international standards. This product serves as a versatile intermediate, enabling chemists to perform selective cross-coupling reactions with high efficiency and yield.

Chemical Properties

The unique substitution pattern of chlorine, fluorine, and iodine on the pyridine ring provides distinct reactivity profiles. This allows for sequential functionalization strategies that are essential in multi-step synthesis routes. The physical characteristics are optimized for handling and storage in standard laboratory environments.

PropertyValue
CAS Number884494-49-9
Molecular FormulaC5H2ClFIN
Molecular Weight257.432
Density2.1±0.1 g/cm3
Boiling Point242.2±35.0 °C at 760 mmHg
Flash Point100.3±25.9 °C

Quality Specifications

Quality assurance is paramount in our production facility. We employ advanced analytical techniques including HPLC and NMR to verify structural integrity and purity levels. Our commitment to excellence ensures that researchers receive materials that perform predictably in sensitive reactions.

  • Appearance: White to light yellow crystalline powder
  • Assay: Greater than or equal to 98.0 percent
  • Moisture Content: Less than or equal to 0.5 percent
  • Packaging: 25 kg per drum or customized according to client requirements

Industrial Applications

This compound is primarily utilized as a key intermediate in the synthesis of active pharmaceutical ingredients. Its halogenated structure supports various catalytic processes such as Suzuki-Miyaura and Heck couplings. These reactions are fundamental in constructing biologically active molecules for drug discovery programs.

Beyond pharmaceuticals, this chemical finds utility in agrochemical research and material science applications where specific pyridine functionalities are required. Our technical team provides support for scaling up processes from laboratory bench to pilot plant operations.

Storage and Handling

To maintain optimal stability, store this product in a cool, ventilated area away from direct sunlight and moisture. Proper handling procedures should be followed according to safety data sheets. We recommend using appropriate personal protective equipment during transfer and weighing operations to ensure personnel safety.

Our logistics network supports global shipping with secure packaging to prevent degradation during transit. Contact our sales team for detailed documentation including certificates of analysis and safety data sheets for regulatory compliance.