2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide
- CAS No.15308-01-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity pharmaceutical intermediate essential for the synthesis of Diclofenac Sodium, offering consistent quality and reliable bulk supply for global API manufacturers.
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Product Overview
2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide is a critical pharmaceutical intermediate primarily utilized in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), specifically serving as a key precursor for Diclofenac Sodium. Our manufacturing process ensures exceptional chemical stability and high purity levels, meeting the rigorous demands of modern API production. This compound features a specific chloroacetamide structure that facilitates efficient downstream reactions, making it an indispensable component for pharmaceutical companies focused on pain management and anti-inflammatory therapeutic solutions.
As a dedicated supplier of fine chemical intermediates, we prioritize consistency and reliability. Each batch undergoes stringent quality control protocols to guarantee that the molecular integrity remains intact during storage and transportation. Our facility is equipped with advanced synthesis capabilities, allowing us to scale production according to client requirements while maintaining compliance with international chemical safety standards.
Technical Specifications
The following table outlines the key physical and chemical properties of this intermediate. These parameters are verified through advanced analytical methods including HPLC and spectroscopy to ensure accuracy.
| Parameter | Specification |
|---|---|
| CAS Number | 15308-01-7 |
| Molecular Formula | C14H10Cl3NO |
| Molecular Weight | 314.59 g/mol |
| Appearance | White or almost white crystalline powder |
| Assay (HPLC) | ≥99.0% |
| Melting Point | 142 - 148°C |
| Loss on Drying | ≤0.5% |
| Total Impurities | ≤1.0% |
| Density | 1.411 g/cm3 |
| Boiling Point | 487.5°C at 760 mmHg |
Industrial Applications
The primary application of 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide is in the pharmaceutical sector, specifically within the manufacturing workflow of Diclofenac Sodium. This intermediate acts as a foundational building block, enabling the construction of the final active pharmaceutical ingredient through controlled acylation and substitution reactions. Its high purity profile minimizes the formation of unwanted by-products, thereby streamlining the purification process for the final drug substance.
Beyond direct API synthesis, this chemical is valuable for research and development teams exploring novel analogues of phenylacetic acid derivatives. The structural characteristics provide a stable platform for further chemical modifications, supporting innovation in medicinal chemistry. Our clients leverage this material to optimize their synthesis routes, reducing overall production costs and improving yield efficiency.
Quality Assurance and Storage
We implement a comprehensive quality management system to oversee every stage of production. From raw material sourcing to final packaging, each step is documented and verified. A Certificate of Analysis (COA) is provided with every shipment, detailing the specific test results for the batch. This transparency ensures that our partners can maintain their own regulatory compliance without interruption.
For optimal preservation, the product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Standard packaging consists of 25 kg drums, though we offer flexible packaging solutions to accommodate specific logistical needs. Proper handling procedures should be followed to maintain the physical integrity of the crystalline powder during transfer and usage.
