Intermediates

2-Chlorobutyric Acid

  • CAS No.4170-24-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chlorobutyric Acid (CAS 4170-24-5), ≥99%, widely used as a key pharmaceutical intermediate in the synthesis of active ingredients such as Levetiracetam.

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Product Technical Details

Product Overview

2-Chlorobutyric Acid is a high-value organic building block extensively employed in the pharmaceutical and fine chemical industries. With a molecular formula of C4H7ClO2 and a molecular weight of 122.55 g/mol, this compound serves as a critical chiral synthon in the production of advanced therapeutic agents, including the antiepileptic drug Levetiracetam (CAS 102767-28-2). Supplied in ≥99% purity, it meets stringent quality standards required for regulated API synthesis.

Specifications

Molecular FormulaC4H7ClO2
Molecular Weight122.55 g/mol
Density1.19 g/cm³
Boiling Point90–92°C at 12 mmHg
Refractive Index1.439
Flash Point76.7°C
AppearanceLight yellow liquid
Purity≥99%
Moisture Content<0.3%
Total Impurities<0.3%

Industrial Applications

As a versatile halogenated carboxylic acid, 2-Chlorobutyric Acid functions primarily as a synthetic intermediate in multi-step pharmaceutical manufacturing. Its reactivity enables efficient construction of carbon-carbon and carbon-heteroatom bonds, making it indispensable in the preparation of complex organic molecules. Key applications include:

  • Synthesis of Levetiracetam and related neurological therapeutics
  • Chiral pool derivatization for enantioselective synthesis
  • Production of specialty agrochemicals and performance materials

Stored in a cool, dry, and tightly sealed container away from moisture, heat, and direct light, this product maintains stability under recommended conditions. Standard packaging is 25 kg in fiber drums, with custom options available to meet GMP and supply chain requirements.