2-(Trifluoromethoxy)benzoic acid
- CAS No.1979-29-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
Premium grade 2-(Trifluoromethoxy)benzoic acid designed for complex organic synthesis workflows. High purity assurance with global shipping availability.
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Product Overview
2-(Trifluoromethoxy)benzoic acid represents a critical fluorinated building block within the realm of advanced organic synthesis. This aromatic carboxylic acid derivative features a unique trifluoromethoxy substituent at the ortho position, imparting distinct electronic and steric properties that are highly valued in modern chemical research. The incorporation of fluorine atoms into organic molecules is a strategic approach used to enhance metabolic stability, modulate lipophilicity, and improve binding affinity in various bioactive compounds.
As a specialized intermediate, this compound serves as a foundational element for the development of sophisticated pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures consistent quality and reliability, making it an ideal choice for research laboratories and industrial production facilities seeking high-performance chemical raw materials.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-(Trifluoromethoxy)benzoic acid |
| CAS Registry Number | 1979-29-9 |
| Molecular Formula | C8H5F3O3 |
| Molecular Weight | 206.12 g/mol |
| Appearance | White to light yellow crystalline powder |
| Purity (Assay) | ≥98.0% |
| Moisture Content | ≤0.2% |
| Melting Point | 78°C |
| Density | 1.206 g/cm3 |
Key Features and Advantages
- High Chemical Purity: Rigorous quality control measures ensure an assay of 98 percent or higher, minimizing impurities that could affect downstream reactions.
- Enhanced Stability: The trifluoromethoxy group provides superior thermal and chemical stability compared to non-fluorinated analogs.
- Versatile Reactivity: Suitable for a wide range of coupling reactions, esterifications, and amide formations commonly used in medicinal chemistry.
- Consistent Supply: Established manufacturing capabilities allow for bulk production and reliable inventory management for long-term projects.
Industrial Applications
This fluorinated intermediate is extensively utilized in the synthesis of complex organic molecules. In the pharmaceutical sector, it acts as a key precursor for developing novel therapeutic candidates where fluorine substitution is required to optimize pharmacokinetic profiles. Researchers leverage its properties to create compounds with improved bioavailability and resistance to enzymatic degradation.
Beyond pharmaceuticals, the compound finds application in agrochemical development, contributing to the creation of advanced pesticides and herbicides with enhanced environmental profiles. Additionally, it is used in materials science for the preparation of specialized polymers and liquid crystals where specific electronic characteristics are necessary. Our team supports clients with technical data and documentation to facilitate seamless integration into their specific synthesis routes.
Quality Assurance and Handling
Every batch undergoes comprehensive testing using advanced analytical techniques such as HPLC and NMR spectroscopy to verify identity and purity. A Certificate of Analysis (COA) is provided with each shipment to ensure full transparency and compliance with international standards. For safe handling, the product should be stored in a cool, ventilated area away from incompatible materials. Standard personal protective equipment is recommended during use to ensure occupational safety.
We offer flexible packaging options, including 25 kg drums, and can accommodate custom requirements based on specific logistical needs. Our global distribution network ensures timely delivery to support your production schedules without interruption.
