(2S)-1-(2-Chloroacetyl)pyrrolidine-2-Carbonitrile
- CAS No.207557-35-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (2S)-1-(2-Chloroacetyl)pyrrolidine-2-Carbonitrile (CAS 207557-35-5) designed for Vildagliptin synthesis. Reliable supply with strict quality control.
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Product Overview
(2S)-1-(2-Chloroacetyl)pyrrolidine-2-Carbonitrile is a specialized chiral pharmaceutical intermediate critical for the synthesis of advanced therapeutic agents, specifically serving as a key precursor in the manufacturing of Vildagliptin. This compound features a distinct pyrrolidine ring structure with a chloroacetyl group and a nitrile functionality, requiring precise stereochemical control during production to ensure the (2S) configuration. Our facility employs state-of-the-art asymmetric synthesis techniques to maintain high enantiomeric excess, ensuring downstream reaction efficiency and final drug safety.
As a dedicated manufacturer, we understand the stringent requirements of the pharmaceutical supply chain. This intermediate is produced under rigorous quality management systems, complying with international standards for chemical purity and impurity profiles. The material is optimized for scalability, supporting both pilot-scale research and large-scale commercial production needs for global pharmaceutical partners.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 207557-35-5 |
| Molecular Formula | C7H9ClN2O |
| Molecular Weight | 172.61 g/mol |
| Appearance | White to Off-white Powder |
| Purity (HPLC) | ≥99.0% |
| Single Impurity | ≤0.1% |
| Moisture Content | ≤0.5% |
| Optical Rotation | Conforms to Standard |
Quality Assurance and Handling
Quality consistency is paramount for intermediates used in active pharmaceutical ingredient (API) synthesis. Each batch of (2S)-1-(2-Chloroacetyl)pyrrolidine-2-Carbonitrile undergoes comprehensive analytical testing, including HPLC, GC, and NMR spectroscopy, to verify chemical identity and purity levels. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting test results against our factory standards. The production environment is controlled to minimize contamination risks, ensuring the material meets the low impurity thresholds required for regulatory submissions.
Proper storage is essential to maintain product stability. The compound should be stored in a cool, dry, and well-ventilated area, away from direct sunlight and moisture sources. Containers must remain tightly sealed when not in use to prevent hydrolysis of the nitrile or chloroacetyl groups. Our packaging solutions are designed to protect the integrity of the chemical during international transit, utilizing durable drums with inner liners suitable for hygroscopic materials.
Industrial Advantages
- High Stereochemical Purity: Ensures efficient downstream chiral synthesis.
- Strict Impurity Control: Single impurity levels maintained below 0.1%.
- Scalable Production: Capable of meeting bulk demand for commercial API manufacturing.
- Global Logistics: Experienced in hazardous chemical shipping and customs clearance.
- Technical Support: Dedicated team available for synthesis route optimization.
We are committed to supporting the pharmaceutical industry with reliable raw materials. By choosing our (2S)-1-(2-Chloroacetyl)pyrrolidine-2-Carbonitrile, partners gain access to a stable supply chain, competitive pricing structures, and the assurance of a compliant manufacturing process. Contact our sales team for current availability, bulk pricing tiers, and sample requests.
