3,4-Difluoro-2-methylbenzoic acid
- CAS No.157652-31-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3,4-Difluoro-2-methylbenzoic acid (CAS 157652-31-8) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical intermediate production.
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Product Overview
3,4-Difluoro-2-methylbenzoic acid is a specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern featuring two fluorine atoms and a methyl group on the benzoic acid scaffold, this chemical offers distinct reactivity profiles essential for constructing complex molecular architectures. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and industrial applications where precision is paramount.
In the realm of medicinal chemistry, fluorinated intermediates are highly valued for their ability to enhance metabolic stability and lipophilicity in drug candidates. This specific benzoic acid derivative provides a versatile platform for further functionalization through various coupling reactions. We adhere to strict quality control protocols to guarantee that every batch meets the rigorous demands of pharmaceutical and agrochemical development pipelines.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 3,4-Difluoro-2-methylbenzoic acid |
| CAS Number | 157652-31-8 |
| Molecular Formula | C8H6F2O2 |
| Molecular Weight | 172.13 g/mol |
| Purity | ≥99.0% |
| Appearance | Off-white to white powder |
| Density | 1.359 g/cm3 |
| Boiling Point | 268oC |
| Flash Point | 115.9oC |
| Refractive Index | 1.511 |
Industrial Applications
This fluorinated benzoic acid derivative is primarily utilized as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals. The presence of fluorine atoms allows for specific electronic modifications that can significantly influence the biological activity of the final product. Common synthetic transformations include amide bond formation, esterification, and cross-coupling reactions such as Suzuki or Buchwald-Hartwig couplings.
Researchers and process chemists value this compound for its stability under various reaction conditions. It serves as a precursor for developing novel therapeutics targeting various disease states, where the fluorine motif is often employed to modulate binding affinity and pharmacokinetic properties. Additionally, it finds application in the production of high-performance materials and specialty chemicals where specific aromatic substitution patterns are required.
Quality Assurance and Packaging
We understand that consistency is vital in chemical manufacturing. Each production lot undergoes comprehensive analysis using advanced spectroscopic and chromatographic methods to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with your internal quality standards. Our facility operates under standardized management systems to maintain product integrity from synthesis to delivery.
Standard packaging consists of 25 kg drums, designed to protect the material from moisture and physical damage during transit. However, we offer flexible packaging solutions tailored to specific customer requirements, including smaller quantities for research purposes or bulk containers for large-scale production. Storage recommendations include keeping the product in a cool, ventilated area away from incompatible substances to maintain stability over extended periods.
