3-Bromo-1,2-Difluoro-4-Nitrobenzene
- CAS No.350699-92-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Bromo-1,2-Difluoro-4-Nitrobenzene liquid for advanced pharmaceutical synthesis. Available in bulk with strict quality control.
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Product Overview
3-Bromo-1,2-Difluoro-4-Nitrobenzene is a highly specialized fluorinated aromatic intermediate designed for complex organic synthesis within the pharmaceutical industry. This compound features a unique substitution pattern containing bromo, difluoro, and nitro functional groups on a benzene ring, making it an invaluable building block for medicinal chemists. The presence of fluorine atoms enhances metabolic stability and bioavailability in downstream drug candidates, while the bromo and nitro groups offer versatile handles for further chemical transformations such as nucleophilic aromatic substitution or cross-coupling reactions.
Our manufacturing process ensures consistent quality and high purity levels suitable for rigorous research and development pipelines. As a trusted global manufacturer, we prioritize strict adherence to international quality standards to support your synthesis projects efficiently.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 3-Bromo-1,2-Difluoro-4-Nitrobenzene |
| CAS Number | 350699-92-2 |
| Molecular Formula | C6H2BrF2NO2 |
| Molecular Weight | 237.99 g/mol |
| Appearance | Light yellow liquid |
| Purity | ≥98.0% |
| Density | 1.89 g/cm3 |
| Boiling Point | 226.7°C at 760 mmHg |
| Flash Point | 90.9°C |
| Refractive Index | 1.556 |
Industrial Applications
This fluorinated intermediate is primarily utilized in the synthesis of advanced pharmaceutical active ingredients. The specific arrangement of substituents allows for selective functionalization, enabling chemists to construct complex molecular architectures required for modern therapeutics. It serves as a critical precursor in the development of compounds targeting various biological pathways.
- Used as a key starting material for nucleophilic substitution reactions.
- Facilitates the introduction of fluorine motifs into drug candidates.
- Compatible with palladium-catalyzed cross-coupling methodologies.
- Supports the development of novel agrochemical and pharmaceutical structures.
Quality Assurance and Handling
We maintain a robust quality control system to ensure every batch meets the specified purity requirements. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing test results against key parameters. Proper handling is essential due to the chemical nature of nitro and halogenated compounds.
Store this material in a tightly closed container within a cool, dry, and well-ventilated area. Keep away from incompatible substances such as strong oxidizing agents or bases. Personal protective equipment including gloves and eye protection should be worn during handling. We offer flexible packing options, typically 25kg per drum, to accommodate various scale requirements from laboratory research to pilot production.
