Intermediates

3-Ethyl-4-methyl-3-pyrrolin-2-one

  • CAS No.766-36-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used primarily in the synthesis of Glimepiride. Available in bulk quantities with full quality documentation.

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Product Technical Details

Product Overview

3-Ethyl-4-methyl-3-pyrrolin-2-one is a highly specialized organic compound recognized for its critical role in modern pharmaceutical synthesis. As a pyrrolinone derivative, this chemical substance serves as an essential building block in the manufacturing of advanced therapeutic agents. Our facility produces this intermediate under strict quality control protocols to ensure consistency and reliability for downstream pharmaceutical applications.

The compound is characterized by its stable chemical structure and high reactivity profile, making it an ideal precursor for complex organic synthesis routes. We understand the importance of purity in pharmaceutical manufacturing, which is why every batch undergoes rigorous analytical testing to meet or exceed industry standards. This commitment to quality ensures that our clients receive materials that facilitate efficient production processes and final product efficacy.

Technical Specifications

ParameterSpecification
CAS Number766-36-9
Molecular FormulaC7H11NO
Molecular Weight125.168 g/mol
AppearanceWhite to light yellow crystalline powder
Assay (HPLC)≥98.0%
Melting Point100-104 °C
Boiling Point279.0±23.0 °C at 760 mmHg
Density1.0±0.1 g/cm3
Flash Point156.6±7.6 °C

Industrial Applications

This intermediate is predominantly utilized in the pharmaceutical industry, specifically serving as a key precursor in the synthesis of Glimepiride. Glimepiride is a well-known third-generation sulfonylurea used in the management of type 2 diabetes mellitus. The quality of the intermediate directly impacts the efficiency and purity of the final active pharmaceutical ingredient (API).

  • Primary precursor for antidiabetic medication synthesis.
  • Utilized in complex organic coupling reactions.
  • Supports large-scale pharmaceutical manufacturing pipelines.
  • Compatible with standard industrial synthesis routes.

Quality Assurance and Safety

We maintain a comprehensive quality management system to guarantee the integrity of 3-Ethyl-4-methyl-3-pyrrolin-2-one. Each production lot is accompanied by a Certificate of Analysis (COA) detailing physical and chemical properties. Our laboratory employs high-performance liquid chromatography (HPLC) and other advanced spectroscopic methods to verify assay purity and identify potential impurities.

Safety is paramount in our operations. This chemical should be handled in accordance with standard laboratory safety procedures. Personnel are advised to use appropriate personal protective equipment during handling to prevent inhalation or skin contact. Our packaging ensures that the product remains protected from moisture and contamination during transit.

Storage and Logistics

To preserve chemical stability, the product should be stored in a cool, ventilated area away from direct sunlight and heat sources. Containers must be kept tightly sealed when not in use to prevent degradation from environmental exposure. We offer flexible packaging options, including standard 25 kg drums, with customization available to meet specific logistical requirements.

Our global supply chain network ensures timely delivery to manufacturers worldwide. Whether you require sample quantities for research and development or bulk volumes for commercial production, we are equipped to support your operational needs with competitive pricing and reliable service.