3-Fluoro-4-iodobenzoic acid
- CAS No.825-98-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Fluoro-4-iodobenzoic acid (CAS 825-98-9) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical research.
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Product Overview
3-Fluoro-4-iodobenzoic acid is a specialized halogenated aromatic compound that serves as a vital building block in modern organic chemistry. This fluorinated benzoic acid derivative combines the unique reactivity of both fluoro and iodo substituents on the benzene ring, making it highly valuable for complex synthetic pathways. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial applications.
The presence of the iodine atom facilitates various cross-coupling reactions, while the fluorine substituent enhances metabolic stability and lipophilicity in downstream pharmaceutical candidates. This dual functionality makes the compound an essential intermediate for medicinal chemists and process development teams working on novel therapeutic agents.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 3-Fluoro-4-iodobenzoic acid |
| CAS Number | 825-98-9 |
| Molecular Formula | C7H4FIO2 |
| Molecular Weight | 266.008 g/mol |
| Appearance | Off-white to light yellow powder |
| Assay | ≥98.0% |
| Density | 2.1±0.1 g/cm3 |
| Boiling Point | 318.5±27.0 °C at 760 mmHg |
| Flash Point | 146.4±23.7 °C |
Industrial Applications
This compound is primarily utilized as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. In drug discovery, it is frequently employed in Suzuki-Miyaura coupling reactions to construct biaryl structures found in many kinase inhibitors and receptor modulators. The fluorine atom provides beneficial electronic effects that can improve the binding affinity and pharmacokinetic properties of the final drug molecule.
Additionally, 3-Fluoro-4-iodobenzoic acid is used in the development of liquid crystals and organic electronic materials where precise halogen substitution patterns are required. Its stability under various reaction conditions allows for versatile synthetic routes, including nucleophilic aromatic substitution and metal-halogen exchange processes. Researchers value this material for its reliability in scale-up operations from laboratory to pilot plant stages.
Quality Assurance And Packaging
We adhere to strict quality control protocols to ensure every batch meets the specified purity standards. Each shipment is accompanied by a comprehensive Certificate Of Analysis (COA) detailing test results for identity, assay, and impurities. Our production facilities operate under standardized management systems to guarantee product consistency and traceability.
Standard packaging consists of 25 kg drums lined with protective materials to prevent moisture uptake and contamination. Custom packaging solutions are available upon request to accommodate specific logistical requirements. We maintain a robust supply chain to ensure timely delivery for global clients engaged in continuous manufacturing processes.
Storage And Handling
To maintain optimal stability, this product should be stored in a cool, ventilated area away from direct sunlight and heat sources. Containers must be kept tightly sealed when not in use to prevent exposure to atmospheric moisture. Proper personal protective equipment should be worn during handling to ensure safety in accordance with standard laboratory practices. For detailed safety information, please refer to the provided Safety Data Sheet (SDS).
