4-(4-Bromo-3-formylphenoxy)benzonitrile
- CAS No.906673-54-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate for Crisaborole synthesis. Available in bulk with comprehensive COA and global shipping options.
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Product Overview
4-(4-Bromo-3-formylphenoxy)benzonitrile is a specialized organic compound serving as a critical building block in the pharmaceutical industry. Primarily recognized for its role in the synthesis of Crisaborole (AN2728), this intermediate facilitates the production of advanced dermatological therapeutics. Our manufacturing process ensures consistent quality, high purity, and reliability for large-scale API production needs.
As a key precursor, this chemical exhibits stable physicochemical properties suitable for complex organic synthesis routes. We maintain strict control over every production batch to meet international regulatory standards, ensuring that downstream manufacturers receive materials that support efficient reaction yields and minimal purification requirements.
Technical Specifications
Quality assurance is paramount in pharmaceutical supply chains. Our facility employs advanced analytical techniques to verify every parameter. The following table outlines the standard specifications and typical test results for this product.
| Items of Analysis | Standard of Analysis | Test Results |
|---|---|---|
| Description | White powder | Conforms |
| Purity | ≥98.0% | 99.20% |
| Water Content | ≤2.0% | N.D. |
| Any Single Impurity | ≤0.5% | 0.40% |
| Total Impurity | ≤2.0% | 0.80% |
| Ethanol Residue | ≤0.3% | 0.05% |
| Conclusion | Conforms to Factory Standard | |
Industrial Applications
This compound is predominantly utilized in the manufacturing of active pharmaceutical ingredients (APIs) targeting inflammatory skin conditions. Its specific structural configuration allows for precise coupling reactions required in the final steps of Crisaborole synthesis. Research and development teams also leverage this intermediate for exploring analogues and derivative compounds within the nitrile and phenoxy chemical families.
Beyond standard API production, this material supports process optimization studies where high purity is essential to reduce catalyst poisoning and side reactions. Our clients range from established pharmaceutical corporations to innovative biotech firms focusing on novel dermatological treatments.
Quality Assurance and Compliance
We operate under a robust quality management system that aligns with global pharmaceutical guidelines. Each batch undergoes rigorous testing using HPLC, GC, and Karl Fischer titration methods. A Certificate of Analysis (COA) is provided with every shipment, detailing full impurity profiles and physical characteristics. We are committed to transparency and traceability throughout the supply chain.
Please note that products under valid patents are not offered to countries covered by such patents. We encourage all partners to verify intellectual property rights within their respective jurisdictions before placing orders. Our compliance team is available to assist with regulatory documentation and audit support.
Packaging and Storage
To maintain stability and integrity, 4-(4-Bromo-3-formylphenoxy)benzonitrile is packaged in secure 25 kg drums. Custom packaging solutions are available upon request to accommodate specific logistical requirements. The product should be stored in a cool, ventilated area away from direct sunlight and moisture. Proper handling procedures ensure safety and preserve chemical potency during transit and warehousing.
