Intermediates

4-Amino-3-Bromobenzotrifluoride

  • CAS No.57946-63-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Amino-3-Bromobenzotrifluoride (CAS 57946-63-1) designed for pharmaceutical synthesis. Reliable supply with comprehensive COA and global shipping capabilities.

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Product Technical Details

Product Overview

4-Amino-3-Bromobenzotrifluoride is a specialized fluorinated organic compound widely recognized for its utility in advanced medicinal chemistry and agrochemical synthesis. As a key building block, this substance features a unique structural arrangement combining an amino group, a bromine substituent, and a trifluoromethyl group on a benzene ring. This specific configuration enhances lipophilicity and metabolic stability in downstream molecular structures, making it highly valuable for the development of novel therapeutic agents.

Our manufacturing process adheres to strict quality control standards to ensure consistent batch-to-batch reproducibility. The compound is synthesized using advanced organic reaction pathways that prioritize high yield and minimal impurity profiles. We understand the critical nature of raw material quality in pharmaceutical development, which is why every production lot undergoes rigorous analytical testing before release.

Technical Specifications

The following table outlines the critical physical and chemical parameters for this product. Our standard specification guarantees a purity level suitable for most research and industrial applications.

ParameterSpecification
Chemical Name4-Amino-3-Bromobenzotrifluoride
CAS Number57946-63-1
Molecular FormulaC7H5BrF3N
Molecular Weight240.02 g/mol
AppearanceWhite to Off-White Crystalline Solid
Purity (HPLC)≥98.0%
Melting Point26-28°C
Boiling Point109-110°C (10 mmHg)
Density1.697 g/cm3

Industrial Applications

This fluorinated aniline derivative serves as a versatile intermediate in the synthesis of complex organic molecules. Its primary application lies within the pharmaceutical sector, where it acts as a precursor for various kinase inhibitors and receptor modulators. The presence of the bromine atom allows for further functionalization through cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling chemists to construct diverse chemical libraries.

Beyond pharmaceuticals, this compound finds utility in the agrochemical industry for developing crop protection agents. The trifluoromethyl group contributes to enhanced biological activity and environmental stability. Researchers utilizing this material benefit from its high reactivity and compatibility with standard organic synthesis protocols. We support both small-scale research quantities and large-scale industrial production requirements.

Quality Assurance and Handling

Quality is the cornerstone of our operation. Each shipment is accompanied by a Certificate of Analysis (COA) detailing the test results against our factory standards. Our quality control team verifies appearance, assay, water content, and other critical parameters to ensure compliance. We maintain a robust supply chain to guarantee timely delivery without compromising product integrity.

For safe handling, store this material in a tightly closed container within a cool, dry, and well-ventilated area. Protect from moisture and direct sunlight to maintain stability. Proper personal protective equipment should be worn during handling to prevent exposure. We are committed to providing safe, compliant, and high-performance chemical solutions to our global partners.