4-Chloro-7-Methoxyquinoline-6-Carboxamide
- CAS No.417721-36-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate for Lenvatinib synthesis. Available in bulk with strict quality control and comprehensive documentation.
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Product Overview
4-Chloro-7-Methoxyquinoline-6-Carboxamide is a specialized pharmaceutical intermediate characterized by its high chemical stability and precise molecular structure. This compound serves as a critical building block in the synthesis of advanced kinase inhibitors, specifically within the oncology therapeutic sector. Our manufacturing process ensures that each batch meets rigorous international standards for purity and consistency, making it an ideal choice for large-scale pharmaceutical production and research applications.
Technical Specifications
We maintain strict quality control protocols to guarantee the reliability of this chemical intermediate. The product is synthesized using advanced organic chemistry techniques, ensuring minimal impurity profiles and high reproducibility. Below are the key technical parameters verified through our internal quality assurance laboratories.
| Parameter | Specification |
|---|---|
| Chemical Name | 4-Chloro-7-Methoxyquinoline-6-Carboxamide |
| CAS Number | 417721-36-9 |
| Molecular Formula | C11H9ClN2O2 |
| Molecular Weight | 236.65 g/mol |
| Purity (HPLC) | ≥98.0% |
| Appearance | White to yellow powder |
Industrial Applications
This quinoline derivative is primarily utilized as a key intermediate in the manufacturing pathway of Lenvatinib, a multi-kinase inhibitor used in the treatment of various cancers. Its specific substitution pattern allows for efficient downstream coupling reactions, facilitating the construction of complex therapeutic molecules. Beyond oncology, derivatives of this structure are also explored in broader medicinal chemistry programs targeting signal transduction pathways.
Quality Assurance and Testing
Every production lot undergoes comprehensive analytical testing including High-Performance Liquid Chromatography (HPLC), Nuclear Magnetic Resonance (NMR), and Mass Spectrometry (MS). We provide a Certificate of Analysis (COA) with every shipment, detailing the specific batch data. Our facility adheres to good manufacturing practices to ensure that the material is safe for use in regulated pharmaceutical environments.
Storage and Handling
To maintain optimal stability, 4-Chloro-7-Methoxyquinoline-6-Carboxamide should be stored in a cool, ventilated area away from direct sunlight and moisture. The material is packaged in secure 25 kg drums, though custom packaging solutions are available to meet specific logistical requirements. Proper personal protective equipment (PPE) is recommended during handling to ensure safety in the laboratory or production setting.
Supply Chain Stability
As a global manufacturer, we offer consistent supply capabilities with flexible logistics options. We understand the critical nature of intermediate supply in pharmaceutical manufacturing and prioritize on-time delivery. Our team is available to discuss custom synthesis routes, scale-up requirements, and long-term supply agreements to support your development pipeline.
