Intermediates

4-Cyanophenylboronic Acid

  • CAS No.126747-14-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Cyanophenylboronic Acid designed for efficient cross-coupling reactions. Reliable supply with comprehensive quality documentation.

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Product Technical Details

Product Overview

4-Cyanophenylboronic Acid represents a critical building block in modern organic synthesis, specifically designed for researchers and industrial manufacturers engaged in complex molecule construction. As a versatile arylboronic acid derivative, this compound serves as an essential reagent in palladium-catalyzed cross-coupling reactions, most notably the Suzuki-Miyaura coupling. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for pharmaceutical process development and large-scale production environments where reliability is paramount.

The compound is characterized by its stability and reactivity profile, which allows for efficient carbon-carbon bond formation under mild conditions. This capability is paramount in the synthesis of biaryl structures found in numerous active pharmaceutical ingredients, agrochemicals, and advanced functional materials. We prioritize purity and safety, delivering a product that meets rigorous international standards for chemical intermediates used in sensitive synthetic pathways.

Technical Specifications

ParameterValue
Chemical Name4-Cyanophenylboronic Acid
CAS Registry Number126747-14-6
Molecular FormulaC7H6BNO2
Molecular Weight146.94 g/mol
Purity Assay>98.0%
Physical AppearanceWhite to Yellow Powder
Melting Point>350 °C
Density1.25 g/cm3
Flash Point169 °C

Industrial Applications

The primary utility of 4-Cyanophenylboronic Acid lies in its role as a coupling partner in transition metal-catalyzed reactions. In medicinal chemistry, it facilitates the rapid assembly of diverse chemical libraries used for drug discovery screening. The cyano group provides a handle for further functionalization, allowing chemists to convert it into amines, amides, or tetrazoles, thereby expanding the chemical space available for lead optimization without compromising the integrity of the core structure.

Beyond pharmaceuticals, this intermediate is utilized in the production of organic light-emitting diodes and other electronic materials where precise molecular architecture is required. Its compatibility with various functional groups makes it a preferred choice for multistep synthesis routes where protecting group strategies are minimized. Our supply chain supports both R and D quantities and bulk industrial demands, ensuring scalability for your projects.

Quality Assurance and Handling

Quality control is integral to our production workflow. Each batch undergoes comprehensive analysis using high-performance liquid chromatography and nuclear magnetic resonance spectroscopy to verify identity and purity. We provide a Certificate of Analysis with every shipment, ensuring transparency and compliance with your internal quality protocols. This documentation is essential for regulatory filings and audit processes within the pharmaceutical industry.

For optimal stability, the product should be stored in a cool, dry environment away from direct light and moisture. Proper sealing is recommended to prevent hydration or degradation over extended periods. Our packaging solutions include durable drums suitable for global logistics, ensuring the material arrives in pristine condition regardless of destination. We also offer customized packaging options to suit specific laboratory or plant requirements.