Intermediates

4-Fluoro-3-nitrobenzoic acid

  • CAS No.453-71-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Fluoro-3-nitrobenzoic acid (CAS 453-71-4) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical intermediates.

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Product Technical Details

Product Overview

4-Fluoro-3-nitrobenzoic acid is a specialized fluorinated aromatic compound widely recognized for its utility in modern organic synthesis. As a key building block, this chemical features both a reactive nitro group and a fluorine substituent on the benzoic acid backbone, enabling diverse transformation pathways. Our manufacturing process ensures consistent molecular integrity, making it an essential precursor for the development of complex pharmaceutical agents and agrochemical formulations.

The presence of the fluorine atom enhances metabolic stability and lipophilicity in downstream drug candidates, while the nitro group serves as a versatile handle for reduction or substitution reactions. We supply this material with a focus on high purity and reliability, catering to research laboratories and industrial production facilities alike.

Key Specifications

Quality control is paramount in the production of fine chemical intermediates. Each batch undergoes rigorous analytical testing to confirm compliance with international standards. The following table outlines the critical physical and chemical parameters guaranteed for this product.

ParameterSpecification
CAS Number453-71-4
Molecular FormulaC7H4FNO4
Molecular Weight185.11 g/mol
AppearancePale yellow powder
Assay (Purity)≥99.0%
Moisture Content≤0.2%
Melting Point125-128°C
Density1.568 g/cm3

Industrial Applications

This compound serves as a critical intermediate in the synthesis of various bioactive molecules. Its primary applications include:

  • Pharmaceutical Synthesis: Used as a starting material for constructing fluorinated drug scaffolds that require enhanced biological activity.
  • Agrochemical Development: Employed in the creation of novel herbicides and pesticides where fluorine substitution improves environmental stability.
  • Organic Coupling Reactions: The carboxylic acid group facilitates amide bond formation, while the nitro group allows for subsequent reduction to aniline derivatives.
  • Nucleophilic Aromatic Substitution: The activated fluorine position enables efficient displacement by nucleophiles under controlled conditions.

Quality Assurance And Storage

We adhere to strict quality management systems to ensure product consistency. Every shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. To maintain stability, the material should be stored in a cool, ventilated environment away from direct sunlight and moisture. Packaging is available in 25 kg drums, with custom options available to meet specific logistical requirements. Our global supply chain ensures timely delivery for large-scale manufacturing needs.