Intermediates

5-Bromo-2-iodopyridine

  • CAS No.223463-13-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Bromo-2-iodopyridine designed for advanced organic synthesis and pharmaceutical intermediate applications with guaranteed quality.

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Product Technical Details

Product Overview

5-Bromo-2-iodopyridine is a highly valued halogenated heterocyclic compound widely utilized in modern medicinal chemistry and agrochemical research. As a versatile building block, this substance features distinct reactivity profiles due to the presence of both bromine and iodine substituents on the pyridine ring. Our manufacturing process ensures exceptional consistency and purity, making it an ideal choice for complex synthetic routes requiring selective cross-coupling reactions.

We specialize in supplying this critical intermediate to pharmaceutical companies and research institutions globally. Each batch undergoes rigorous quality control testing to meet international standards, ensuring reliable performance in downstream applications. Our commitment to excellence supports innovation in drug discovery and material science.

Key Chemical Properties

The unique structural arrangement of 5-Bromo-2-iodopyridine allows for selective functionalization. The carbon-iodine bond is generally more reactive than the carbon-bromine bond, enabling chemists to perform sequential coupling reactions. This selectivity is crucial for constructing complex molecular architectures efficiently. The compound exhibits stable physical properties under standard storage conditions, facilitating safe handling in laboratory and industrial settings.

Our production facility adheres to strict safety and environmental protocols. We utilize advanced purification techniques to remove impurities that could interfere with sensitive catalytic processes. This attention to detail results in a product that delivers reproducible results across various synthetic methodologies.

Technical Specifications

ParameterSpecification
CAS Number223463-13-6
Molecular FormulaC5H3BrIN
Molecular Weight283.89 g/mol
AppearanceLight brown to brown crystalline powder
Purity (GC)≥99.0%
Melting Point113-117oC
Boiling Point258.8oC
Density2.347 g/cm3

Industrial Applications

This compound serves as a pivotal intermediate in the synthesis of numerous pharmaceutical agents. It is frequently employed in Suzuki-Miyaura, Heck, and Sonogashira coupling reactions. Researchers utilize this building block to develop novel therapies targeting various diseases, including oncology and neurological disorders. The high purity grade we provide minimizes side reactions, optimizing yield and reducing waste in production scales.

Beyond pharmaceuticals, 5-Bromo-2-iodopyridine finds applications in agrochemical development and functional material science. Its stability and reactivity make it suitable for creating specialized polymers and ligands. Our team works closely with clients to understand specific project requirements, offering tailored solutions for bulk procurement and custom packaging needs.

Quality Assurance and Storage

Quality is paramount in our operations. Every shipment includes a comprehensive Certificate of Analysis (COA) detailing test results against specified parameters. We maintain a robust supply chain to ensure timely delivery without compromising product integrity. Proper storage is essential to maintain stability over time.

We recommend storing this material in a cool, ventilated place away from direct sunlight and moisture. Containers should remain tightly sealed when not in use to prevent degradation. Our packaging options include 25 kg drums or custom configurations based on client logistics. For further technical support or pricing inquiries, our sales team is ready to assist with prompt and professional service.