5-Fluorouracil
- CAS No.51-21-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 5-Fluorouracil (CAS 51-21-8) supplied for pharmaceutical manufacturing. Certified quality with comprehensive COA and bulk availability.
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Product Overview
5-Fluorouracil, commonly known as 5-FU, is a critical pyrimidine analog utilized extensively within the pharmaceutical industry. As a specialized chemical intermediate, this compound serves as a foundational building block for various oncology therapeutic formulations. Our manufacturing facility ensures that every batch meets rigorous international standards for purity and consistency, making it suitable for licensed pharmaceutical production and advanced research applications.
We understand the stringent requirements associated with cytotoxic compounds. Therefore, our production lines are designed to handle such materials with the utmost care, ensuring safety for workers and integrity for the product. The chemical structure, defined as 5-fluoropyrimidine-2,4-dione, allows for specific interactions in nucleotide synthesis pathways, which is why high-quality sourcing is essential for downstream drug development.
Technical Specifications
Quality control is the cornerstone of our supply chain. Each shipment of 5-Fluorouracil is accompanied by a detailed Certificate of Analysis (COA). The following table outlines the key physical and chemical parameters that define our standard grade material:
| Parameter | Specification | Typical Result |
|---|---|---|
| Appearance | White or off-white crystalline powder | Conform |
| Assay (HPLC) | ≥99.0% | 99.15% |
| Loss on Drying | ≤0.5% | 0.11% |
| Residue on Ignition | ≤0.1% | 0.03% |
| Heavy Metals | ≤20ppm | Conform |
| Fluorine Content | 13.9% - 15.0% | 14.35% |
Industrial Applications
This chemical is primarily employed as an active pharmaceutical ingredient (API) or a key intermediate in the synthesis of antineoplastic agents. It functions by inhibiting thymidylate synthase, thereby interrupting DNA and RNA synthesis in rapidly dividing cells. Beyond direct formulation, it is also used to synthesize derivatives such as 5-fluorocytosine. Our clients include licensed pharmaceutical manufacturers and research institutions focused on oncology therapeutics.
We support our partners with technical data packages that facilitate regulatory filings. Whether you require this material for generic drug production or novel compound research, our grade ensures performance benchmarking against global standards. We offer flexibility in packaging to suit pilot-scale trials or full commercial manufacturing runs.
Quality Assurance and Safety
Operating under GMP-inspired guidelines, our quality assurance team conducts multi-stage testing. This includes raw material verification, in-process controls, and final product validation. We maintain full traceability for every batch produced. Safety data sheets (SDS) are provided with every order to ensure compliant handling and storage within your facility.
Proper storage is vital to maintain stability. The product should be kept in a cool, ventilated area away from direct sunlight and moisture. We recommend using sealed containers to prevent degradation. Our logistics team is experienced in handling regulated chemical shipments globally, ensuring timely delivery while adhering to all transportation safety regulations.
Why Choose Our Supply
- Consistent high purity levels exceeding 99 percent
- Comprehensive documentation including COA and MSDS
- Scalable production capacity for bulk requirements
- Strict compliance with international chemical safety standards
- Dedicated technical support for formulation queries
Partner with us for a reliable source of 5-Fluorouracil. We are committed to supporting the pharmaceutical industry with safe, compliant, and high-quality chemical solutions.
