6-Bromohexanoyl chloride
- CAS No.22809-37-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 6-Bromohexanoyl chloride (CAS 22809-37-6) serves as a vital building block for pharmaceutical and organic synthesis applications.
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Product Overview
6-Bromohexanoyl chloride is a highly versatile organic intermediate characterized by its dual functional groups, featuring both a reactive acyl chloride moiety and a terminal bromoalkyl chain. This unique chemical structure makes it an indispensable reagent in the construction of complex molecular architectures. As a key building block, it facilitates nucleophilic substitution and acylation reactions, enabling chemists to introduce specific carbon chain lengths and functional handles into target molecules. Our manufacturing process ensures consistent quality and high purity, meeting the rigorous demands of modern pharmaceutical research and industrial organic synthesis.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 22809-37-6 |
| Molecular Formula | C6H10BrClO |
| Molecular Weight | 213.50 g/mol |
| Purity | ≥98.0% |
| Moisture Content | ≤0.25% |
| Total Impurities | ≤0.3% |
| Appearance | Colorless to pale yellow liquid |
Physical and Chemical Properties
The physical properties of 6-Bromohexanoyl chloride are critical for handling and process design. It exhibits a density of approximately 1.395 g/mL at 25 degrees Celsius, indicating a relatively heavy liquid structure due to the presence of bromine and chlorine atoms. The boiling point is recorded at 130 degrees Celsius under 20 mm Hg pressure, requiring vacuum distillation for purification. With a flash point exceeding 230 degrees Fahrenheit, it maintains stability under standard storage conditions but requires careful handling away from ignition sources. The refractive index is typically around 1.486, serving as a key identifier for quality control during production batches.
Industrial Applications
This compound is primarily utilized as a strategic intermediate in the synthesis of pharmaceutical active ingredients and fine chemicals. The bromo group allows for further functionalization via substitution reactions, while the acyl chloride group enables amide or ester bond formation. Common applications include the development of novel therapeutic agents, polymer modifiers, and specialized agrochemicals. Researchers value this reagent for its reliability in forming carbon-nitrogen and carbon-oxygen bonds, making it a staple in medicinal chemistry laboratories focused on structure-activity relationship studies.
Quality Assurance and Safety
We adhere to strict quality management systems to ensure every batch meets specified purity levels. Each shipment is accompanied by a Certificate of Analysis (COA) verifying physical constants and chemical composition. Regarding safety, this substance is corrosive and moisture-sensitive. It must be stored in a tightly closed container within a cool, dry, and well-ventilated area, segregated from incompatible substances such as strong oxidizers and bases. Proper personal protective equipment, including gloves and eye protection, is mandatory during handling to prevent exposure to vapors or liquid contact.
