Intermediates

6-Fluoro-2-Methyl-3-Nitropyridine

  • CAS No.18605-16-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 6-Fluoro-2-Methyl-3-Nitropyridine (CAS 18605-16-8) designed for advanced pharmaceutical synthesis and organic chemistry applications.

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Product Technical Details

Product Overview

6-Fluoro-2-Methyl-3-Nitropyridine is a specialized fluorinated heterocyclic compound that serves as a critical building block in modern medicinal chemistry and organic synthesis. As a key pharmaceutical intermediate, this substance enables the construction of complex molecular architectures required for the development of novel therapeutic agents. Our manufacturing process ensures exceptional consistency and reliability, making it an ideal choice for research laboratories and industrial production facilities alike.

The presence of the fluorine atom at the sixth position significantly enhances the metabolic stability and lipophilicity of downstream drug candidates. This chemical profile is highly sought after in the design of kinase inhibitors and other targeted therapies. We adhere to strict quality management systems to guarantee that every batch meets the rigorous demands of global pharmaceutical standards.

Technical Specifications

Quality control is paramount in the production of fine chemical intermediates. Our facility utilizes advanced analytical instrumentation, including HPLC and NMR spectroscopy, to verify identity and purity. The following table outlines the standard physical and chemical properties associated with this product grade.

ParameterSpecification
CAS Number18605-16-8
Molecular FormulaC6H5FN2O2
Molecular Weight156.12 g/mol
AppearanceWhite Crystalline Powder
Purity≥99.0%
Density1.357 g/mL at 25 °C
Boiling Point233 °C at 760 mmHg
Flash Point94.7 °C
Refractive Index1.538

Industrial Applications

This fluorinated pyridine derivative is primarily utilized as a precursor in the synthesis of active pharmaceutical ingredients (APIs). Its unique reactivity profile allows for diverse functionalization strategies, including nucleophilic aromatic substitution and cross-coupling reactions. Researchers value this compound for its stability under various reaction conditions and its compatibility with sensitive catalytic systems.

  • Essential building block for heterocyclic drug synthesis.
  • Used in the development of neurological and cardiovascular therapeutics.
  • Suitable for custom organic synthesis and process research.
  • Supports large-scale manufacturing with consistent supply chains.

Storage and Handling

To maintain optimal quality, 6-Fluoro-2-Methyl-3-Nitropyridine should be stored in a tightly closed container within a cool, dry, and well-ventilated area. Protection from moisture and direct sunlight is recommended to prevent degradation. Standard laboratory safety protocols apply, including the use of appropriate personal protective equipment during handling. We provide comprehensive safety data sheets (SDS) and certificates of analysis (COA) with every shipment to ensure regulatory compliance and user safety.

Packaging and Logistics

Our standard packaging configuration consists of 25 kg drums, designed for secure international transport. Custom packaging solutions are available upon request to accommodate specific logistical requirements. As a global manufacturer, we offer reliable shipping services to ensure timely delivery to our partners worldwide. Contact our sales team for detailed information regarding bulk pricing and lead times.