6-Methyl-5-nitro-1H-pyridin-2-one
- CAS No.28489-45-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 6-Methyl-5-nitro-1H-pyridin-2-one (CAS 28489-45-4), a versatile pyridine-based intermediate for advanced organic synthesis in pharmaceutical and agrochemical R&D.
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Product Overview
6-Methyl-5-nitro-1H-pyridin-2-one is a high-value heterocyclic compound belonging to the substituted pyridinone family. With its distinct nitro and hydroxyl functional groups positioned on a methylated pyridine ring, this molecule serves as a critical building block in multi-step organic syntheses. It is widely employed in the development of complex pharmaceutical active ingredients and specialty agrochemicals due to its reactivity and structural versatility.
Specifications
| Molecular Formula | C6H6N2O3 |
|---|---|
| Molecular Weight | 154.12 g/mol |
| CAS Number | 28489-45-4 |
| Appearance | Light brown to brown crystalline powder |
| Assay | ≥98.0% |
| Moisture | ≤0.5% |
| Melting Point | 230–232°C |
| Density | 1.36 g/cm³ |
| Boiling Point | 326.4°C |
| Flash Point | 151.2°C |
Industrial Applications
This compound is primarily utilized as an intermediate in fine chemical manufacturing. Its applications include:
- Serving as a key precursor in the synthesis of bioactive molecules targeting neurological and metabolic pathways.
- Functioning as a scaffold in medicinal chemistry for constructing novel kinase inhibitors and antimicrobial agents.
- Acting as a functionalized core in the development of crop protection agents with enhanced selectivity.
Due to its electron-deficient aromatic system, it readily participates in nucleophilic substitution, reduction, and cross-coupling reactions, making it indispensable in modern synthetic routes.
Handling and Storage
Store in a cool, dry, and well-ventilated area away from heat sources and incompatible materials. Keep container tightly closed when not in use. Standard industrial hygiene practices should be followed during handling. Packaging is typically provided in 25 kg drums, with custom options available upon request.
