Intermediates

7-Hydroxy-3,4-dihydro-1H-quinolin-2-one

  • CAS No.22246-18-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in the synthesis of Aripiprazole. Available in bulk quantities with full COA support and global shipping.

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Product Technical Details

Product Overview

Welcome to our comprehensive product profile for 7-Hydroxy-3,4-dihydro-1H-quinolin-2-one. This specialized pharmaceutical intermediate plays a pivotal role in the modern synthesis of advanced therapeutic agents. Identified by CAS number 22246-18-0, this compound is meticulously manufactured to meet the rigorous demands of the global pharmaceutical industry. Our production facilities adhere to strict quality management systems, ensuring that every batch delivers consistent performance and reliability for downstream processing. We understand the critical nature of supply chain continuity in drug manufacturing and maintain strategic stock levels to support our partners.

Key Specifications

ParameterValue
Chemical Name7-Hydroxy-3,4-dihydro-1H-quinolin-2-one
CAS Number22246-18-0
Molecular FormulaC9H9NO2
Molecular Weight163.173
AppearanceOff-white powder
Assay≥98.0%
Melting Point232-237°C
Loss on Drying≤0.5%
Residue on Ignition≤1.0%
Total Impurities≤1.0%

Industrial Applications

The primary application of this chemical entity is serving as a crucial building block in the synthesis of Aripiprazole, a widely recognized atypical antipsychotic medication. The precision required in this synthesis pathway demands intermediates of exceptional quality to ensure the safety and efficacy of the final drug product. By utilizing our graded material, pharmaceutical manufacturers can streamline their regulatory filings and ensure product safety. We support our clients with full documentation, including Certificates of Analysis and Method Validation reports, facilitating smoother audit processes and compliance with international standards such as GMP and ISO.

Quality Control And Testing

Maintaining high purity levels is essential to prevent side reactions during the manufacturing of active pharmaceutical ingredients. Our technical team focuses on optimizing crystallization and purification processes to minimize impurities. This attention to detail guarantees that the material performs predictably in reaction vessels, reducing waste and improving overall yield for our partners. Each batch undergoes rigorous testing using advanced analytical techniques including HPLC and NMR to verify structural integrity and purity profiles. We commit to transparency by providing detailed test results with every shipment.

Storage And Logistics

Storage and handling require standard precautions for fine chemical powders. The material should be kept in a cool, ventilated environment away from direct sunlight and moisture. Proper sealing is crucial to maintain stability over extended periods. We offer flexible packaging solutions, typically supplying in 25 kg drums, but can customize according to specific logistical requirements. Our global shipping network ensures timely delivery to major pharmaceutical hubs across Asia, Europe, and the Americas. We work with trusted logistics partners to ensure safe and compliant transport of all chemical materials.

Why Choose Our Supply

  • Consistent batch-to-batch reproducibility for reliable production scaling.
  • Competitive bulk pricing structures designed for long-term partnerships.
  • Dedicated technical support team available for synthesis optimization queries.
  • Robust production scheduling to prevent supply chain disruptions.
  • Commitment to safety and environmental responsibility throughout manufacturing.