Chloromethyl Isopropyl Carbonate
- CAS No.35180-01-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Chloromethyl Isopropyl Carbonate (CAS 35180-01-9) designed for pharmaceutical synthesis, specifically as a key intermediate for Tenofovir production.
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Product Overview
Chloromethyl Isopropyl Carbonate is a specialized organic compound widely recognized for its critical role in the pharmaceutical industry. As a high-efficiency alkylating agent, this chemical serves as an essential building block in the synthesis of complex nucleotide analogs. Our manufacturing process ensures that every batch meets rigorous international standards, providing a reliable foundation for downstream drug production. The compound is characterized by its stable chemical structure and high reactivity, making it ideal for precise organic synthesis operations.
We understand the importance of consistency in pharmaceutical manufacturing. Therefore, our production facilities adhere to strict quality control protocols. Each lot undergoes comprehensive testing to verify identity, purity, and physical properties. This commitment to excellence ensures that our clients receive a product that performs predictably in their specific synthesis routes, minimizing variability and maximizing yield in final API production.
Technical Specifications
The following table outlines the key physical and chemical parameters for Chloromethyl Isopropyl Carbonate. These specifications are guaranteed for every shipment, supported by a Certificate of Analysis (COA).
| Parameter | Specification |
|---|---|
| Chemical Name | Chloromethyl Isopropyl Carbonate |
| CAS Number | 35180-01-9 |
| Molecular Formula | C5H9ClO3 |
| Molecular Weight | 152.58 g/mol |
| Appearance | Colorless clear liquid or slightly yellow transparent liquid |
| Purity (GC) | ≥99.0% |
| Moisture Content | ≤0.5% |
| Density | 1.15 g/cm3 |
| Boiling Point | 147.5°C |
| Flash Point | 48°C |
| Refractive Index | 1.42 |
Applications and Usage
The primary application of Chloromethyl Isopropyl Carbonate is in the synthesis of antiviral medications. It acts as a crucial intermediate in the manufacturing process of Tenofovir, a widely used nucleotide reverse transcriptase inhibitor. The high purity level of our product ensures that impurities do not interfere with the delicate coupling reactions required in nucleotide analog synthesis. This is vital for maintaining the safety and efficacy profiles of the final pharmaceutical product.
Beyond antiviral applications, this carbonate derivative is utilized in various organic synthesis pathways where chloromethylation is required. Its compatibility with standard industrial solvents and reaction conditions makes it a versatile reagent for research and development laboratories as well as large-scale production facilities. Our technical team can provide guidance on optimal storage and handling to maintain stability during your manufacturing process.
Quality Assurance and Safety
Safety and quality are paramount in our operations. We implement a multi-stage quality assurance system that includes raw material inspection, in-process control, and final product verification. Impurity profiles are closely monitored, with total impurities kept below 1.0% and any individual impurity limited to 0.3%. This level of control is essential for meeting regulatory requirements in global markets.
Regarding safety, Chloromethyl Isopropyl Carbonate should be handled with care. It is recommended to store the product in a cool, ventilated place away from direct sunlight and heat sources. The packaging consists of 200 kg drums, designed to prevent contamination and ensure safe transport. We also offer flexible packaging solutions according to specific customer requirements. Our global logistics network ensures timely delivery while maintaining the integrity of the chemical throughout the supply chain.
