Intermediates

Methyl 2-(2-Amino-1,3-Thiazol-4-Yl)acetate

  • CAS No.64987-16-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used primarily in the synthesis of cephalosporin antibiotics like cefotiam. Available in bulk quantities with full COA.

Request Bulk Pricing

Product Technical Details

Product Overview

Methyl 2-(2-Amino-1,3-Thiazol-4-Yl)acetate is a critical pharmaceutical intermediate recognized for its high stability and reactivity in organic synthesis. This compound serves as a foundational building block in the manufacturing of advanced cephalosporin antibiotics, specifically playing a vital role in the production chain of cefotiam. Our facility ensures that every batch meets stringent international quality standards, providing pharmaceutical manufacturers with a reliable source for their synthesis requirements.

As a specialized chemical entity, this thiazole derivative exhibits excellent solubility characteristics and consistent molecular integrity. The production process involves rigorous purification steps to eliminate impurities that could affect downstream reaction yields. We understand the importance of supply chain consistency in the pharmaceutical industry, which is why we maintain substantial inventory levels to support continuous manufacturing operations globally.

Technical Specifications

ParameterSpecification
CAS Number64987-16-2
Molecular FormulaC6H8N2O2S
Molecular Weight172.21 g/mol
AppearanceWhite to beige solid
Purity≥99.0%
Melting Point112-116°C
Density1.353 g/cm³
Refractive Index1.589

Industrial Applications

The primary application of this intermediate lies in the synthesis of beta-lactam antibiotics. Its unique chemical structure allows for efficient coupling reactions necessary for constructing the complex side chains found in modern cephalosporins. Pharmaceutical companies utilize this material to ensure the final drug product meets bioavailability and efficacy standards required by regulatory bodies.

Beyond antibiotic synthesis, this compound is occasionally employed in research and development settings for creating novel thiazole-based derivatives. Its versatility makes it a valuable asset for medicinal chemistry teams exploring new therapeutic pathways. We support both large-scale commercial production and smaller R&D batches with equal commitment to quality and documentation.

Quality Assurance and Storage

Quality control is paramount in our manufacturing process. Each production lot undergoes comprehensive testing using high-performance liquid chromatography and nuclear magnetic resonance spectroscopy to verify structural integrity and purity levels. A Certificate of Analysis is provided with every shipment, detailing all relevant physical and chemical properties.

  • Packaged in 25 kg drums or according to specific customer requirements.
  • Stored in a cool, ventilated environment away from direct sunlight.
  • Protected from moisture and incompatible substances during transit.
  • Full traceability from raw materials to finished goods.

Proper storage conditions are essential to maintain the stability of this intermediate. We recommend keeping containers tightly sealed when not in use to prevent degradation. Our logistics team ensures that all shipments are handled according to international safety regulations, guaranteeing that the product arrives in optimal condition for immediate use in your synthesis processes.