Methyl 2-cyanoisonicotinate
- CAS No.94413-64-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used in the synthesis of Topiroxostat. Available in bulk quantities with strict quality control and comprehensive documentation.
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Product Overview
Methyl 2-cyanoisonicotinate is a specialized organic compound recognized for its stability and reactivity in complex synthetic pathways. As a key pyridine derivative, this substance serves as an essential building block in the pharmaceutical industry, particularly for the construction of heterocyclic structures required in advanced therapeutic agents. Our facility produces this intermediate under stringent Good Manufacturing Practice (GMP) guidelines to ensure consistency and reliability for downstream processing.
The compound is characterized by its distinct crystalline structure and high thermal stability, making it suitable for various reaction conditions. We prioritize the delivery of materials that meet exacting standards, facilitating efficient synthesis routes for our global partners. Each batch undergoes rigorous analytical testing to verify identity and potency before release.
Technical Specifications
Quality control is paramount in the production of fine chemical intermediates. The following table outlines the critical physical and chemical parameters guaranteed for this product. Our laboratory utilizes high-performance liquid chromatography (HPLC) and other advanced spectroscopic methods to validate these specifications.
| Parameter | Specification |
|---|---|
| Chemical Name | Methyl 2-cyanoisonicotinate |
| CAS Number | 94413-64-6 |
| Molecular Formula | C8H6N2O2 |
| Molecular Weight | 162.15 g/mol |
| Appearance | White Crystalline Powder |
| Purity (HPLC) | ≥99.0% |
| Melting Point | 107-109℃ |
| Loss on Drying | ≤2.0% |
| Heavy Metals | ≤10 ppm |
| Total Impurity | ≤0.5% |
Industrial Applications
This intermediate is primarily utilized in the multi-step synthesis of active pharmaceutical ingredients (APIs). Specifically, it acts as a precursor in the manufacturing of Topiroxostat, a notable xanthine oxidase inhibitor. The cyano and ester functional groups present on the pyridine ring allow for versatile chemical transformations, including hydrolysis, reduction, and coupling reactions.
Chemists value this material for its predictable reactivity profile, which minimizes side reactions and optimizes overall yield in scale-up processes. Whether used in research and development or commercial production, Methyl 2-cyanoisonicotinate provides a reliable foundation for creating complex molecular architectures.
Quality Assurance and Packaging
We understand that contamination control is critical in pharmaceutical synthesis. Our production environment is designed to prevent cross-contamination, and every lot is accompanied by a Certificate of Analysis (COA). The product is packaged in durable, moisture-resistant containers to maintain integrity during transit.
Standard packaging includes 25kg cardboard drums, though we accommodate custom requirements based on logistical needs. Storage recommendations include keeping the container tightly closed in a cool, dry, and well-ventilated area away from incompatible substances. Our logistics team ensures global shipping compliance, providing safety data sheets and all necessary documentation for customs clearance.
