N-(3-chloropropyl)dibutylamine
- CAS No.36421-15-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity N-(3-chloropropyl)dibutylamine (CAS 36421-15-5) for pharmaceutical synthesis, offering ≥98% purity and strict quality control. Ideal as a key intermediate in regulated API manufacturing with global bulk supply options.
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Product Overview
N-(3-chloropropyl)dibutylamine is a critical aliphatic amine intermediate extensively employed in advanced pharmaceutical synthesis. This compound, with the molecular formula C11H24ClN and a molecular weight of 205.77 g/mol, demonstrates exceptional reactivity and stability for constructing complex molecular architectures. As a versatile building block, it facilitates the production of high-value active pharmaceutical ingredients under stringent cGMP guidelines. Our manufacturing process ensures batch-to-batch consistency, meeting the exacting demands of global pharmaceutical developers requiring reliable starting materials for scale-up operations.
Technical Specifications
| Molecular Formula | C11H24ClN |
|---|---|
| Molecular Weight | 205.77 g/mol |
| Density | 0.899 g/cm3 |
| Boiling Point | 253.2 °C at 760 mmHg |
| Flash Point | 106.9 °C |
| Refractive Index | 1.45 |
| Appearance | Light yellow to colorless liquid |
| Purity | ≥98% |
| Water Content | ≤1.0% |
| Maximum Impurity | ≤0.5% |
Key Features and Benefits
- Exceptional purity profile ensuring minimal side reactions in sensitive syntheses
- Rigorous QC protocols with comprehensive certificate of analysis (COA) for every batch
- Optimized stability for extended storage without degradation
- Scalable production capacity supporting multi-ton annual requirements
- Compliance with international pharmacopeial standards for pharmaceutical intermediates
Industrial Applications
This intermediate serves as a fundamental precursor in the synthesis of cardiovascular therapeutics, particularly for manufacturing dronedarone hydrochloride (CAS 141625-93-6) and related antiarrhythmic agents. Its chemical structure enables efficient alkylation reactions in multi-step API production, contributing to the formation of critical molecular scaffolds. Pharmaceutical manufacturers rely on this compound for developing high-purity neurological and cardiac medications under strict regulatory oversight. The compound's reactivity profile makes it indispensable for constructing quaternary ammonium motifs in complex drug molecules, while maintaining excellent yield characteristics in industrial-scale processes.
Packaging and Storage
Supplied in 25 kg hermetically sealed cardboard drums with moisture-resistant liners, ensuring product integrity during global logistics. Storage requires cool, dry conditions below 25°C in tightly closed containers, protected from light and humidity to maintain stability. Shelf life exceeds 24 months when stored per specifications, with detailed handling guidelines provided in the technical dossier. All shipments include safety data sheets compliant with GHS regulations and full traceability documentation for audit purposes.
