N-(5H-Purin-6-yl)benzamide
- CAS No.4005-49-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity N-(5H-Purin-6-yl)benzamide pharmaceutical intermediate designed for advanced organic synthesis and nucleoside analog development.
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Product Overview
N-(5H-Purin-6-yl)benzamide, frequently recognized in chemical literature as N6-Benzoyladenine, represents a critical purine derivative utilized extensively within the pharmaceutical and fine chemical sectors. This compound features a benzoyl protective group attached to the adenine backbone, making it an indispensable building block for the synthesis of complex nucleosides and nucleotides. Our manufacturing process ensures exceptional structural integrity and chemical stability, providing researchers and industrial partners with a reliable foundation for developing advanced therapeutic agents.
As a key intermediate in medicinal chemistry, this substance plays a vital role in the construction of antiviral and anticancer drug candidates. The high level of purification achieved during production minimizes downstream processing challenges, allowing for more efficient reaction yields in subsequent synthetic steps. We adhere to strict quality control protocols to guarantee that every batch meets rigorous international standards for pharmaceutical raw materials.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 4005-49-6 |
| Molecular Formula | C12H9N5O |
| Molecular Weight | 239.23 g/mol |
| Appearance | White or almost white crystalline powder |
| Assay (HPLC) | ≥99.0% |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤10 ppm |
| Melting Point | 242-244°C |
Industrial Applications
The primary application of N-(5H-Purin-6-yl)benzamide lies in the field of organic synthesis, specifically serving as a precursor for modified nucleosides. These derivatives are essential in the research and development of new pharmaceutical compounds targeting viral replication and cellular proliferation. Due to its protected amine structure, it offers superior reactivity control during glycosylation reactions, which is crucial for creating stereoselective nucleoside analogs.
Beyond pharmaceutical synthesis, this chemical is utilized in academic research institutions for studying purine metabolism and enzyme kinetics. Its high purity profile makes it suitable for sensitive analytical applications where impurity interference must be eliminated. Manufacturers leveraging this intermediate benefit from streamlined production workflows and consistent batch-to-batch reproducibility.
Quality Assurance and Storage
Quality is paramount in our production facility. Each lot undergoes comprehensive testing using high-performance liquid chromatography (HPLC) and ultraviolet spectroscopy (UV) to verify identity and potency. We provide a Certificate of Analysis (COA) with every shipment, ensuring full transparency and compliance with regulatory requirements. Our packaging solutions are designed to maintain product integrity during global transit.
For optimal stability, the material should be stored in a cool, ventilated environment away from direct sunlight and moisture sources. Standard packaging includes 25 kg drums, though we offer flexible customization to meet specific logistical needs. By choosing our supply chain, partners gain access to a dependable source of high-grade chemical intermediates supported by decades of industry expertise.
